右佐匹克隆加重曲唑酮的肝毒性致急性肝损伤1例报告

武彤; 马仁舒; 辛桂杰; 高润平; 于鸽

doi:10.3969/j.issn.1001-5256.2020.09.033

右佐匹克隆加重曲唑酮的肝毒性致急性肝损伤1例报告

DOI: 10.3969/j.issn.1001-5256.2020.09.033

吉林大学第一医院肝胆胰内科

基金项目:

2019年吉林大学第一医院第十届院青年基金项目(JDYY102019005)；

详细信息

中图分类号: R575
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出版历程
- 出版日期: 2020-09-20

Eszopiclone aggravates liver injury caused by trazodone hepatotoxicity: A case report

Department of Hepatology, The First Hospital of Jilin University

Research funding:

摘要

摘要:
<正>1病例资料患者女性,53岁,因"发现乙型肝炎病原学阳性36年,腹胀、乏力1年,加重伴纳差7 d",于2019年11月12日入本院。患者36年前体检发现乙型肝炎病原学阳性,未诊治。2018年8月患者出现腹胀、乏力,肝酶学正常,HBV DNA 1.81×106IU/ml,肝脏瞬时弹性成像5.2 kP a,未规范治疗,后规律复查肝功能均未见异常。7 d前患者腹胀、乏力症状加重,伴有纳差,肝功能酶学指标明显升高。既往:有乙型肝炎家族史,母亲为HBV携带者,2001年出现"焦虑、恐惧、寐差",确诊为"神经官能症",
- 化学性与药物性肝损伤 /
- 曲唑酮 /
- 右佐匹克隆 /
- 细胞色素P-450 CYP3A
- chemical and drug induced liver injury /
- trazodone /
- eszopiclone /
- cytochrome P-450 CYP3A

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参考文献(15)

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