The current situation of pancreatic cancer is that the etiology is not clear and prevention is impossible. The sensitivity and specificity of the auxiliary detection methods are low,and early diagnosis is a worldwide problem. The efficacy of existing treatment methods is not satisfactory,and it is difficult to break through in a short time. The overall 5-year survival rate is only 7. 2%. In the face of the current situation of pancreatic cancer,the solution to the key problems is to strengthen basic research,explore its etiology and pathogenesis,remove the cause,cut off the path of occurrence and development,which is the only correct way to overcome pancreatic cancer. It is an important way to significantly improve the efficacy by developing peripheral blood,urine detection technology with high sensitivity and specificity,imaging diagnosis technology,and improving the early diagnosis rate. However,the research on basic and early diagnostic techniques takes a long time and costs a lot,which makes it difficult to achieve results in a short time. Therefore,the problem to be solved urgently is to develop a personalized treatment plan through standardized MDT,optimized combination of existing diagnosis and treatment methods,so as to achieve the purpose of improving the efficacy. This expert consensus is developed from the first edition,which is based on the diagnosis and treatment status of pancreatic cancer and the dilemma that is difficult to break through in a short time,with reference to the successful diagnosis and treatment experience at home and abroad,combined with the national conditions of our country,after repeated deliberation,discussion and revison by many well-known experts in the domestic industry. This consensus discusses the meaning and purpose,the main tasks,the necessary objective conditions for carrying out,workflows,precautions,relevant clinical and basic research of MDT,multi-center MDT and eMDT mode exploration in detail. Through the formulation and publication of this consensus,we hope that it can help to promote the standardized development of pancreatic cancer MDT and improve the efficacy of pancreatic cancer in China,to summarize successful experience and promote international exchanges,to strengthen personnel training and echelon construction,to formulate relevant policies and promote the development of MDT in the whole country. This consensus is expert consensus on the MDT model developed in China,which is not only applicable to pancreatic cancer,but also can be used as a reference for other tumors.