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非酒精性脂肪性肝病与结直肠腺瘤性息肉的相关性分析

钏莉雪 常江 赵锦涵 李洛华 杨旭瑶 余荻

引用本文:
Citation:

非酒精性脂肪性肝病与结直肠腺瘤性息肉的相关性分析

DOI: 10.3969/j.issn.1001-5256.2020.06.022
基金项目: 

昆明医科大学2019年研究生创新基金(2019S164); 

详细信息
  • 中图分类号: R575.5;R735.34

Association between nonalcoholic fatty liver disease and colorectal adenomatous polyps

Research funding: 

 

  • 摘要:

    目的探讨非酒精性脂肪性肝病(NAFLD)与结直肠腺瘤性息肉的相关性及NAFLD严重程度与结直肠腺瘤性息肉发生风险的关系。方法选取2019年3月-2019年8月在昆明医科大学第二附属医院消化内科住院的结直肠腺瘤性息肉患者67例为腺瘤组,另选取同期就诊的结肠镜检查正常或病理学检查为炎性、增生性息肉者45例为对照组。比较2组基线资料及肝受控衰减参数(CAP)的差异。根据FibroTouch检测结果将所有研究对象分为无脂肪肝组及轻度、中度、重度NAFLD组,分析NAFLD严重程度与结直肠腺瘤性息肉发病风险的关系。正态分布的计量资料两组间比较采用t检验;多组间比较采用单因素方差分析,进一步两两比较采用LSD-t检验。非正态分布的计量资料两组间比较采用Mann-Whitney U检验;多组间比较采用Kruskal-Wallis H检验,进一步两两比较采用Nemenyi法。计数资料组间比较采用χ2检验。采用logistic回归分析结直肠腺瘤的危险因素。结果腺瘤组中男性(51. 11%vs 73. 13%,χ2=5. 687,P=0. 017)、年龄[(56...

     

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