背胰和腹胰源性胰头癌的临床病理特征差异

王大松; 叶辉

doi:10.3969/j.issn.1001-5256.2019.11.048

背胰和腹胰源性胰头癌的临床病理特征差异

DOI: 10.3969/j.issn.1001-5256.2019.11.048

王大松,
叶辉

四川大学华西医院胆道外科

详细信息

中图分类号: R735.9
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出版历程
- 收稿日期: 2019-06-30
- 出版日期: 2019-11-20

Differences in the clinicopathological features of pancreatic head carcinoma arising from the dorsal pancreas and the ventral pancreas

Wang DaSong,
Ye Hui

Department of Biliary Surgery,West China Hospital,Sichuan University

摘要

摘要: 胰腺由背胰和腹胰融合而来,背胰形成胰头腹侧部、胰颈、胰体、胰尾,而腹胰则形成胰头背侧部和胰腺钩突;背胰和腹胰之间存在着融合平面,可以通过对胰多肽进行免疫组化染色的方法识别该融合平面。背胰和腹胰源性胰头癌在局部侵袭、淋巴结转移和神经侵袭,以及生存时间等方面存在差异。主要就背胰、腹胰源性胰头癌的临床病理差异进行综述。
- 胰腺肿瘤 /
- 病理状态,体征和症状 /
- 消化系统外科手术
Abstract: The pancreas arises from the dorsal and ventral anlagen. The dorsal anlagen forms the cephalic part of the head of the pancreas,the neck of the pancreas,the body of the pancreas,and the tail of the pancreas,while the ventral anlagen forms the caudal part of the head of the pancreas and the uncinate process of the pancreas. There is a fusion plane between the dorsal pancreas and the ventral pancreas,which can be identified by immunohistochemical staining of pancreatic polypeptide. There are differences in local invasion,lymph node metastasis,neural invasion,and survival time between pancreatic head carcinoma arising from the dorsal pancreas and that arising from the ventral pancreas. This article reviews the differences in clinicopathological features between these two types of pancreatic head carcinoma.
- pancreatic neoplasms /
- pathological conditions,signs and symptoms /
- digestive system surgical procedures

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参考文献(25)

[1] SIEGEL RL,MILLER KD,JEMAL A. Cancer statistics,2018[J]. CA Cancer J Clin,2018,68(1):7-30.

[2] CHEN W,SUN K,ZHENG R,et al. Cancer incidence and mortality in China,2014[J]. Chin J Cancer Res,2018,30(1):1-12.

[3] CHEN W. Cancer statistics:Updated cancer burden in China[J]. Chin J Cancer Res,2015,27(1):1.

[4] HIDALGO M. Pancreatic cancer[J]. N Engl Med,2010,362(17):1605-1617.

[5] SIRRI E,CASTRO FA,KIESCHKE J,et al. Recent trends in survival of patients with pancreatic cancer in germany and the united states[J]. Pancreas,2016,45(6):908-914.

[6] BASTURK O,COBAN I,ADSAY NV. Pancreatic cysts pathologic classification,differential diagnosis,and clinical implications[J]. Arch Pathol Lab Med,2009,133(3):423-438.

[7] Pancreatic Cancer Committee of Chinese Anti-Cancer Association. Comprehensive guidelines for the diagnosis and treatment of pancreatic cancer(2018 version)[J]. J Clin Hepatol,2018,34(10):2109-2120.(in Chinese)中国抗癌协会胰腺癌专业委员会．胰腺癌综合诊治指南(2018版)[J]．临床肝胆病杂志，2018,34(10):2109-2120.

[8] YIN HY. Effects of pancreactomy on stress indicators in pancreatic cancer patients[J]. Trauma and Crit Medicine,2018,6(6):404-405.(in Chinese)尹皓宇．胰腺癌全胰切除对患者应激指标影响[J]．创伤与急危重病医学，2018,6(6):404-405.

[9] TANG RF,ZHANG FR,WANG SX,et al. Clinicopathological characteristics of ductal adenocarcinomas arising from the ventral and dorsal pancreas[J]. Chin J Gen Surg,2004,19(2):28-30.(in Chinese)唐瑞峰，张风瑞，王顺祥，等．腹胰或背胰发生的胰头癌在临床病理特点及预后上的差异[J]．中华普通外科杂志，2004,19(2):28-30.

[10] RADI M,GAUBERT R,CRISTOL-GAUBERT M,et al. A 3D reconstruction of pancreas development in the human embryos during embryonic period(Carnegie stages 15-23)[J]. Surg Radiol Anat,2010,32(1):11-15.

[11] TADOKORO H,KOZU T,TOKI F,et al. Embryological fusion between the ducts of the ventral and dorsal primordia of the pancreas occurs in two manners[J]. Pancreas,1997,14(4):407-414.

[12] KITAGAWA H,OHTA T,MAKINO I,et al. Carcinomas of the ventral and dorsal pancreas exhibit different patterns of lymphatic spread[J]. Front Biosci,2008,13:2728-2735.

[13] LIU FJ,CHENG YS. Advances in imaging diagnosis of pancreatic cancer[J]. World Chin J Dig,2010,18(5):495-501.(in Chinese)刘峰君，程英升．胰腺癌影像诊断新进展[J]．世界华人消化杂志，2010,18(5):495-501.

[14] OKAMURA Y,FUJII T,KANZAKI A,et al. Clinicopathologic assessment of pancreatic ductal carcinoma located at the head of the pancreas,in relation to embryonic development[J]. Pancreas,2012,41(4):582-588.

[15] MAKINO I,KITAGAWA H,OHTA T,et al. Nerve plexus invasion in pancreatic cancer:Spread patterns on histopathologic and embryological analyses[J]. Pancreas,2008,37(4):358-365.

[16] ZHU CF,SUN BC,ZUO GP,et al. Research progress of pancreatic head cancer arising from dorsal and ventral pancreas[J]. Chin J Dig Surg,2017,16(10):1084-1086.(in Chinese)朱春富，孙倍成，左国平，等．背胰和腹胰源性胰头癌的研究进展[J]．中华消化外科杂志，2017,16(10):1084-1086.

[17] YANG YC,LI YX. The surgical treatment of pancreatic cancer:History and present state[J]. Chin J Gen Surg,2018,27(3):269-283.(in Chinese)杨永超，李宜雄．胰腺癌外科治疗的历史和现状[J]．中国普通外科杂志，2018,27(3):269-283.

[18] LI SJ,HU JH,XIE YZ,et al. Relation between clinicopathologic factors and prognosis of pancreatic head cancer following radical resection[J]. Chin J Gen Surg,2014,21(8):965-970.(in Chinese)李诗杰，胡军红，谢永铮，等．根治性切除胰头癌患者临床病理资料与预后的关系[J]．中国普外基础与临床杂志，2014,21(8):965-970.

[19] RIEDIGER H,KECK T,WELLNER U,et al. The lymph node ratio is the strongest prognostic factor after resection of pancreatic cancer[J]. J Gastrointest Surg,2009,13(7):1337-1344.

[20] DURCZYNSKI A,HOGENDORF P,SZYMANSKI D,et al. Sentinel lymph node mapping in tumors of the pancreatic body:Preliminary report[J]. Wspolczesna Onkol,2012,16(3):206-209.

[21] SALOMAN JL,ALBERS KM,RHIM AD,et al. Can stopping nerves,stop cancer[J]. Trends Neurosci,2016,39(12):880-889.

[22] PATEL BN,OLCOTT E,JEFFREY RB. Extrapancreatic perineural invasion in pancreatic adenocarcinoma[J]. Abdom Radiol(NY),2018,43(2):323-331.

[23] YI SQ,MIWA K,OHTA T,et al. Innervation of the pancreas from the perspective of perineural invasion of pancreatic cancer[J]. Pancreas,2003,27(3):225-229.

[24] HAO DY,A SL,ZHAO JG,et al. Analysis on postoperative complications and survival prognosis of radical resection of pancreatic cancer combined with portal vein/superior mesenteric vein resection[J]. J Clin Exp Med,2019,18(17):1894-1896.(in Chinese)郝德彦，阿斯楞，赵建国，等．联合门静脉/肠系膜上静脉切除重建的胰腺癌根治术术后并发症及生存预后分析[J]．临床和实验医学杂志，2019,18(17):1894-1896.

[25] GLEBOVA NO,HICKS CW,TOSOIAN J,et al. Outcomes of arterial resection during pancreatectomy for tumor[J]. J Vasc Surg,2016,63(3):722-729.

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