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原发性胆汁性胆管炎/自身免疫性肝炎重叠综合征早期治疗获组织学缓解1例报告

王静 赵黎莉 石瑞芳 刘勇钢 李嘉

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原发性胆汁性胆管炎/自身免疫性肝炎重叠综合征早期治疗获组织学缓解1例报告

DOI: 10.3969/j.issn.1001-5256.2019.09.037
详细信息
  • 中图分类号: R575

Early treatment of PBC-AIH overlap syndrome with histological remission: A case report

  • 摘要: <正>1病例资料患者男性,42岁,主因"发现肝功能异常1个月"于2014年8月21日入本院。患者平素无乏力、厌食、皮肤瘙痒等不适。既往体健,否认肝病史及其他系统疾病史,否认饮酒史,否认家族性遗传病史。入院查体:生命体征平稳,BMI 23. 03 kg/m~2,正常面容,无色素沉着,可见肝掌,未见蜘蛛痣,无皮肤、巩膜黄

     

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    [2] Working Subgroup (English version) for Clinical Practice Guidelines for Primary Biliary Cirrhosis. Guidelines for the management of primary biliary cirrhosis:The intractable hepatobiliary disease study group supported by the ministry of health, labour and welfare of Japan[J]. Hepatol Res, 2014, 44 (Suppl 1) :71-90.
    [3] European Association for the Study of the Liver. EASL clinical practice guidelines:Management of cholestatic liver diseases[J]. J Hepatol, 2009, 51 (2) :237-267.
    [4] WANG TT, LU CL, FAN XL, et al. Clinical and pathological features of autoimmune hepatitis-primary biliary cholangitis overlap syndrome versus autoimmune hepatitis:An analysis of107 patients undergoing liver biopsy[J]. J CIin Hepatol, 2017, 33 (11) :2179-2185. (in Chinese) 王婷婷, 鲁昌立, 凡小丽, 等.自身免疫性肝炎-原发性胆汁性胆管炎重叠综合征的临床及病理学特征分析[J].临床肝胆病杂志, 2017, 33 (11) :2179-2185.
    [5] MARTNEZ CO, DAZ RG, MARN ZJ, et al. Autoimmune hepatitis-primary biliary cholangitis overlap syndrome. Longterm outcomes of a retrospective cohort in a university hospital[J]. Gastroenterol Hepatol, 2018, 41 (9) :544-552.
    [6] Expert committee on the 2015 update of expert consensus on the diagnosis and treatment of cholestatic liver disease. Expert consensus on the diagnosis and treatment of cholestatic liver disease:An update in 2015[J]. J Clin Hepatol, 2015, 31 (10) :1563-1574. (in Chinese) 胆汁淤积性肝病诊断治疗专家共识2015年更新专家委员会.胆汁淤积性肝病诊断治疗专家共识:2015年更新[J].临床肝胆病杂志, 2015, 31 (10) :1563-1574.
    [7] MAKINO T, OHTAKE N, WATANABE A, et al. Down-regulation of a hepatic transporter multidrug resistance-associated protein 2 is involved in alteration of pharmacokinetics of glycyrrhizin and its metabolites in a rat model of chronic liver injury[J]. Drug Metab Dis, 2008, 36 (7) :1438-1443.
    [8] WU XH. Efficacy of compound glycyrrhizin in treatment of facial hormone-dependent dermatitis[J]. J Front Med, 2016, 6 (12) :318-319. (in Chinese) 武小红.复方甘草酸苷治疗面部激素依赖性皮炎的疗效观察[J].医药前沿, 2016, 6 (12) :318-319.
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  • 出版日期:  2019-09-20
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