多发性肌炎误诊为自身免疫性肝病1例报告

张利娟; 高银杰; 周霞; 贺希; 冯丹妮; 张达利; 刘鸿凌

doi:10.3969/j.issn.1001-5256.2019.08.033

多发性肌炎误诊为自身免疫性肝病1例报告

DOI: 10.3969/j.issn.1001-5256.2019.08.033

解放军总医院第五医学中心原肝移植中心

基金项目:

首都市民健康培育(Z16110000116058)；三〇二医院基金项目(YNKT2014006)；

详细信息

中图分类号: R685.2
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出版历程
- 出版日期: 2019-08-20

Polymyositis misdiagnosed as autoimmune liver disease: A case report

Liver Transplantation Center, The Fifth Medical Center, General Hospital of PLA

Research funding:

摘要

摘要: <正>多发性肌炎是特发性炎性肌病最常见的类型之一,临床表现为对称性肌无力,肌酸激酶(CK)、乳酸脱氢酶(LDH)水平升高,自身抗体阳性[1]。自身免疫性肝病是自身免疫反应引起的慢性肝脏炎症,可导致肝功能异常,伴随自身抗体阳性。多发性肌炎可导致转氨酶升高,因此易误诊为自身免疫性肝病,同时存在上述两种疾病患者少见。现对1例多发性肌炎患者报道如下。1病例资料患者女性,16岁,因"乏力3个月"于2017年11月8日入
- 多发性肌炎 /
- 误诊
- polymyositis /
- diagnostic errors

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参考文献(15)

[1] FINDLAY AR, GOYAL NA, MOZAFFAR T. An overview of polymyositis and dermatomyositis[J]. Muscle Nerve, 2015, 51 (5) :638-656.

[2] van de VLEKKERT J, HOOGENDIJK JE, de VISSER M. Myositis with endomysial cell invasion indicates inclusion body myositis even if other criteria are not fulfilled[J]. Neuromuscul Disord, 2015, 25 (6) :451-456.

[3] MILISENDA JC, SELVA-O’CALLAGHAN A, GRAU JM. The diagnosis and classification of polymyositis[J]. J Autoimmun, 2014, 48-49:118-121.

[4] BOHLMEYER TJ, WU AH, PERRYMAN MB. Evaluation of laboratory tests as a guide to diagnosis and therapy of myositis[J]. Rheum Dis Clin North Am, 1994, 20 (4) :845-856.

[5] MATHUR T, MANADAN AM, THIAGARAJAN S, et al. Serum transaminases are frequently elevated at time of diagnosis of idiopathic inflammatory myopathy and normalize with creatine kinase[J]. J Clin Rheumatol, 2014, 20 (3) :130-132.

[6] JEPSEN P, GRNBK L, VILSTRUP H. Worldwide incidence of autoimmune liver disease[J]. Dig Dis, 2015, 33 (Suppl 2) :2-12.

[7] HENEGHAN MA, YEOMAN AD, VERMA S, et al. Autoimmune hepatitis[J]. Lancet, 2013, 382 (9902) :1433-1444.

[8] WANG TT, LU CL, FAN XL, et al. Clinical and pathological features of autoimmune hepatitis-primary biliary cholangitis overlap syndrome versus autoimmune hepatitis[J]. J Clin Hepatol, 2017, 33 (11) :2179-2185. (in Chinese) 王婷婷, 鲁昌立, 凡小丽, 等.自身免疫性肝炎-原发性胆汁性胆管炎重叠综合征的临床及病理学特征分析[J].临床肝胆病杂志, 2017, 33 (11) :2179-2185.

[9] OHIRA H, ABE K, TAKAHASHI A. Involvement of the liver in rheumatic diseases[J]. Clin J Gastroenterol, 2012, 5 (1) :9-14.

[10] ZIERDEN M, KHNEN E, ODENTHAL M, et al. Effects and regulation of autoreactive CD8+T cells in a transgenic mouse model of autoimmune hepatitis[J]. Gastroenterology, 2010, 139 (3) :975-986.

[11] MATSUMOTO T, KOBAYASHI S, SHIMIZU H, et al. The liver in collagen diseases:Pathologic study of 160 cases with particular reference to hepatic arteritis, primary biliary cirrhosis, autoimmune hepatitis and nodular regenerative hyperplasia of the liver[J]. Liver, 2000, 20 (5) :366-373.

[12] TJRNLUND A, TANG Q, WICK C, et al. Abatacept in the treatment of adult dermatomyositis and polymyositis:A randomised, phase IIb treatment delayed-start trial[J]. Ann Rheum Dis, 2018, 77 (1) :55-62.

[13] TERZIROLI BERETTA-PICCOLI B, MIELI-VERGANI G, VERGANI D. Autoimmune hepatitis:Standard treatment and systematic review of alternative treatments[J]. World J Gastroenterol, 2017, 23 (33) :6030-6048.

[14] FLORES A, MAYO MJ. Primary biliary cirrhosis in 2014[J].Curr Opin Gastroenterol, 2014, 30 (3) :245-252.

[15] LI QQ, ZHOU XM, QI XS, et al. Recommendations for The British Society of Gastroenterology/UK-PBC primary biliary cholangitis treatment and management guidelines (2018) [J]. J Clin Hepatol, 2018, 34 (6) :1191-1192. (in Chinese) 李谦谦, 周新苗, 祁兴顺, 等.《2018年英国胃肠病学会/英国PBC协作组原发性胆汁性胆管炎治疗及管理指南》推荐意见[J].临床肝胆病杂志, 2018, 34 (6) :1191-1192.

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