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硬皮病合并肝结节病1例报告

张雨 邵玥明 殷鑫 高卉 许芳 金清龙 温晓玉

引用本文:
Citation:

硬皮病合并肝结节病1例报告

DOI: 10.3969/j.issn.1001-5256.2019.07.033
基金项目: 

吉林省科技计划项目(20190201065JC); 

详细信息
  • 中图分类号: R593.2;R575

Scleroderma with hepatic sarcoidosis: A case report

Research funding: 

 

  • 摘要: <正>硬皮病是一种以皮肤局限性或弥漫性增厚和纤维化为特征的全身性结缔组织病,除皮肤外还可累及内脏。结节病是一种以非干酪肉芽肿为特征的系统性疾病,感染、药物、自身免疫等都可能是本病病因,肺部和淋巴结最常累及,肝脏是第三大常见的累及器官,临床表现缺乏特异性[1-2]。两种疾病很少在同一患者身上被发现,易被漏诊、误诊。现分享1例硬皮病合并肝结节病患者的诊治过程,以加深临床医生对这两种疾病的认识。

     

  • [1]PETERS B, VANHOENACKER FM, BEMARD P, et al.Hepatosplenic sarcoidosis complicated by liver cirrhosis[J].J Belg Soc Radiol, 2015, 99 (2) :53-57.
    [2]SYED U, ALKHAWAM H, BAKHIT M, et al.Hepatic sarcoidosis:pathogenesis, clinical context, and treatment options[J].Scand J Gastroenterol, 2016, 51 (9) :1025-1030.
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    [4]ZHANG JX, LI YX, WANG HY.A retrospective analysis of the primary symptom and the first visiting department of 66 cases with sarcoidosis[J].J Cardiovascular Pulmonary Dis, 2018, 37 (1) :29-32. (in Chinese) 张健雄, 李云霄, 王浩彦.66例结节病首发表现与首诊科室回顾分析[J].心肺血管病杂志, 2018, 37 (1) :29-32.
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    [7]MODARESI ESFEH J, CULVER D, PLESEC T, et al.Clinical presentation and protocol for management of hepatic sarcoidosis[J].Expert Rev Gastroenterol Hepatol, 2015, 9 (3) :349-358.
    [8]UNGPRASERT P, CROWSON CS, SIMONETTO DA, et al.Clinical characteristics and outcome of hepatic sarcoidosis:Apopulation-based study 1976-2013[J].Am J Gastroenterol, 2017, 112 (10) :1556-1563.
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    [11]REN XX, HOU SW, MA W, et al.A case of systemic scleroderma with skin sarcoidosis[J].J Clin Dermatol, 2014, 43 (5) :290-292. (in Chinese) 任新新, 侯绍伟, 马伟, 等.系统性硬皮病并发皮肤结节病[J].临床皮肤科杂志, 2014, 43 (5) :290-292.
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  • 出版日期:  2019-07-20
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