肝纤维化和肝硬化逆转的组织学评价

郑永见; 汪艳

doi:10.3969/j.issn.1001-5256.2019.04.002

肝纤维化和肝硬化逆转的组织学评价

DOI: 10.3969/j.issn.1001-5256.2019.04.002

郑永见,
汪艳

器官衰竭防治国家重点实验室广东省肝纤维化工程技术研究中心南方医科大学肝病研究所

基金项目:

国家自然科学基金(81670522)；广州市科技计划项目(201607020019)；

详细信息

中图分类号: R575.2
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- 文章访问数: 1892
- HTML全文浏览量: 35
- PDF下载量: 485
- 被引次数: 0
出版历程
- 收稿日期: 2019-01-02
- 出版日期: 2019-04-20

Histological assessment of reversal of liver fibrosis and cirrhosis

State Key Laboratory of Organ Failure Research, Guangdong Provincial Research Center for Liver Fibrosis, Institute of Hepatology, Southern Medical University, Central Laboratory of Southern Medical University, Southern Medical University

Research funding:

摘要

摘要: 肝纤维化的诊断为慢性肝病的治疗决策和预后评价等提供了重要依据。随着治疗学的飞速进步,各类新的临床问题纷纷涌现,对肝纤维化诊断技术的需求也不断更新。目前多数情况下,组织学评价仍是慢性肝病肝纤维化和肝硬化明确诊断的最可靠方式。基于主要临床文献数据,分析和讨论了组织学评价在当前慢性肝病管理和临床研究中诊断肝纤维化/肝硬化及其逆转的应用价值及研发方向。
- 肝硬化 /
- 肝炎,慢性 /
- 脂肪肝 /
- 组织学
Abstract: Liver fibrogenesis is a common pathway of pathological progression of chronic liver injuries. The diagnosis of liver fibrosis provides an important basis for treatment decision-making and prognostic evaluation of chronic liver diseases. With the rapid development of therapeutics, many new clinical issues have emerged, which requires new techniques for the diagnosis of liver fibrosis. At present, histological assessment remains the most reliable method for a definite diagnosis of liver fibrosis and cirrhosis. With reference to related clinical articles and data, this article analyzes the clinical value and research directions of histological assessment in chronic liver disease management and diagnosis of liver fibrosis/cirrhosis and its reversal.
- liver cirrhosis /
- hepatitis, chronic /
- fatty liver /
- histology

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