HCV相关性华氏巨球蛋白血症和冷球蛋白血症1例报告

于小源; 辛奇; 刘英敏; 靳凤艳

doi:10.3969/j.issn.1001-5256.2019.03.029

HCV相关性华氏巨球蛋白血症和冷球蛋白血症1例报告

DOI: 10.3969/j.issn.1001-5256.2019.03.029

1. 吉林大学第一医院血液科
2. 吉林大学第一医院肝胆外科

详细信息

中图分类号: R512.63;R733
计量
- 文章访问数: 928
- HTML全文浏览量: 16
- PDF下载量: 304
- 被引次数: 0
出版历程
- 出版日期: 2019-03-20

Hepatitis C virus-associated Waldenstrom macroglobulinemia and cryoglobulinemia: A case report

Department of Hematology, The First Hospital of Jilin University

摘要

摘要:
<正>华氏巨球蛋白血症（Waldenstro9m macroglobulinemia,WM）是一种少见的惰性成熟B细胞淋巴瘤,在非霍奇金淋巴瘤中所占比例<2%[1-2]。WM患者同时出现冷球蛋白血症更为罕见,可能与HCV感染有关。1病例资料患者女性,65岁,以"双下肢水肿、乏力3个月,腹胀1个月"于2017年2月20日入肾内科诊治。既往有镶牙史。查体可见腹部膨隆,周身水肿,双下肢重度压凹性水肿。入院后查
- Waldenstrom巨球蛋白血症 /
- 冷球蛋白血症 /
- 肝炎病毒属 /
- 病例报告
- Waldenstrom macroglobulinemia /
- cryoglobulinemia /
- hepacivirus /
- case reports

HTML全文

参考文献(13)

[1] LI J. Advances in diagnosis and treatment of giant globuline-mia—interpretation of lymphocytic lymphoma/giant globuline-mia diagnosis and treatment in China (2016 edition) [J]. JClin Hematol, 2017, 30 (5) :677-679. (in Chinese) 李剑.华氏巨球蛋白血症的诊治进展———“淋巴浆细胞淋巴瘤/华氏巨球蛋白血症诊断与治疗中国专家共识 (2016年版) ”解读[J].临床血液学杂志, 2017, 30 (5) :677-679.

[2] CAO XX, MENG Q, CAI H, et al. Evaluation of clinical character-istics, MYD88L265Pmutation, CXCR4WHIMmutation and prognosis inWaldenstrm macroglobulinemia:A single center retrospectivestudy of 93 patients[J]. Chin J Hematol, 2017, 38 (6) :494-498. (in Chinese) 曹欣欣, 孟琦, 蔡昊, 等.华氏巨球蛋白血症患者的临床特征、MYD88L265P、CXCR4WHIM突变和预后:单中心93例回顾性分析[J].中华血液学杂志, 2017, 38 (6) :494-498.

[3] WANG H, CHEN Y, LI F, et al. Temporal and geographic varia-tions of Waldenstrom macroglobulinemia incidence:A large popu-lation-based study[J]. Cancer, 2012, 118 (15) :3793-3800.

[4] OLSZEWSKI AJ, TREON SP, CASTILLO JJ. Evolution of manage-ment and outcomes in Waldenstrm macroglobulinemia:A popu-lation-based analysis[J]. Oncologist, 2016, 21 (11) :1377-1386.

[5] NIPP R, MITCHELL A, PISHKO A, et al. Waldenstrom macro-globulinemia in hepatitis C:Case report and review of the cur-rent literature[J]. Case Rep Oncol Med, 2014, 2014:165670.

[6] ZHANG YF, NIE QH. HCV-associated cryoglobulinemia[J].J Pract Hepatol, 2006, 9 (1) :56-58. (in Chinese) 张亚飞, 聂青和.丙型肝炎病毒相关性冷球蛋白血症[J].实用肝脏病杂志, 2006, 9 (1) :56-58.

[7] ZHANG W. Lymphoma with cryoglobulinemia[J]. J Inter In-tens Med, 2017, 23 (2) :95-98. (in Chinese) 张薇.淋巴瘤合并冷球蛋白血症[J].内科急危重症杂志, 2017, 23 (2) :95-98.

[8] LAUER GM, WALKER BD. Hepatitis C virus infection[J]. NEngl J Med, 2001, 345 (1) :41-52.

[9] AN G, QI JY, QIU LG. Hepatitis C virus-associated lympho-proliferative disease[J]. Int J Blood Transfus Hemat, 2008, 31 (2) :178-182. (in Chinese) 安刚, 齐军元, 邱录贵.丙肝病毒相关淋巴增殖性疾病[J].国际输血及血液学杂志, 2008, 31 (2) :178-182.

[10] MACHIDA K, CHENG KT, PAVIO N, et al. Hepatitis C virusE2-CD81 interaction induces hypermutation of the immuno-globulin gene in B cells[J]. J Virol, 2005, 79 (13) :8079-8089.

[11] SAADOUN D, LANDAU DA, CALABRESE LH, et al. HepatitisC-associated mixed cryoglobulinaemia:A crossroad be-tween autoimmunity and lymphoproliferation[J]. Rheumatolo-gy (Oxford) , 2007, 46 (8) :1234-1242.

[12] MARTYAK LA, YEGANEH M, SAAB S. Hepatitis C and lym-phoproliferative disorders:From mixed cryoglobulinemia tonon-Hodgkin's lymphoma[J]. Clin Gastroenterol Hepatol, 2009, 7 (8) :900-905.

[13] ZHANG W, FENG J. Diagnosis and treatment of Waldenstrom'smacroglobulinemia[J]. J Int Concepts Pract, 2017, 12 (5) :309-313. (in Chinese) 张薇, 冯俊.华氏巨球蛋白血症的诊断与治疗[J].内科理论与实践, 2017, 12 (5) :309-313.

施引文献

资源附件(0)

访问统计