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胆汁淤积导致肝纤维化的机制及其阻断策略

陈瑞玲 马雄

引用本文:
Citation:

胆汁淤积导致肝纤维化的机制及其阻断策略

DOI: 10.3969/j.issn.1001-5256.2019.02.002
详细信息
  • 中图分类号: R575.22

Pathogenesis of cholestasis-induced liver fibrosis and thoughts for blockade

  • 摘要:

    胆汁淤积是指胆汁流形成、分泌和排泄障碍的一种病理状态,而肝纤维化是肝损伤引起的组织修复过程。胆汁淤积性肝病是由胆汁淤积、胆管渐进性破坏和肝内炎症持续存在所导致的一种慢性肝病,引起胆管细胞和肝细胞损伤,并逐步进展为肝纤维化。结合目前的研究进展,对胆汁淤积导致肝纤维化的发生机制和阻断策略作一综述。

     

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  • 收稿日期:  2018-11-07
  • 出版日期:  2019-02-20
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