钆塞酸二钠在肝细胞癌诊断中的价值

李若坤; 严福华; 李克

doi:10.3969/j.issn.1001-5256.2018.07.003

钆塞酸二钠在肝细胞癌诊断中的价值

DOI: 10.3969/j.issn.1001-5256.2018.07.003

1. 上海交通大学医学院附属瑞金医院放射科
2. 复旦大学附属华山医院放射科

详细信息

中图分类号: R735.7
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出版历程
- 收稿日期: 2018-04-11
- 出版日期: 2018-07-20

Value of Gd-EOB-DPTA in the diagnosis of hepatocellular carcinoma

Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine

摘要

摘要: 钆塞酸二钠（Gd-EOB-DTPA）是一种具有双对比成像功能的肝胆特异性对比剂,既可以通过动态增强反映病灶血供信息,还可以通过肝胆特异期成像反映肝细胞膜分子受体表达变化。Gd-EOB-DTPA能够多维度反映肝硬化结节多步癌变信息,提高乏血供肝细胞癌（HCC）及小肝癌的检出率,显示高危肝硬化结节,已被多项国内外临床实践指南用于HCC的无创性诊断。就Gd-EOB-DTPA在HCC中的诊断价值作一论述。
- 癌,肝细胞 /
- 钆塞酸二钠 /
- 诊断
Abstract: Gd-EOB-DPTA is a hepatocyte-specific contrast agent with the function of double-contrast imaging. It can reflect the blood supply of lesions via dynamic enhancement imaging and show the change in the expression of molecular receptors on hepatocyte membrane via hepatobiliary phase imaging. Gd-EOB-DPTA can reflect the multistep process of hepatocarcinogenesis from multiple dimensions, improve detection of hypovascular hepatocellular carcinoma ( HCC) and small HCC, display cirrhotic nodules with high-risk malignant transformation, and therefore, it has been recommended as a noninvasive tool for HCC diagnosis in China and international HCC clinical practice guidelines. This article reviews the recent advances of Gd-EOB-DTPA in the diagnosis of HCC.
- carcinoma, hepatocellular /
- gadoxetic acid /
- diagnosis

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参考文献(28)

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