中文English
ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R

留言板

尊敬的读者、作者、审稿人, 关于本刊的投稿、审稿、编辑和出版的任何问题, 您可以本页添加留言。我们将尽快给您答复。谢谢您的支持!

姓名
邮箱
手机号码
标题
留言内容
验证码

胰十二指肠切除术后营养支持效果及安全性的Meta分析

张宝华 杨亚 龚建平

引用本文:
Citation:

胰十二指肠切除术后营养支持效果及安全性的Meta分析

DOI: 10.3969/j.issn.1001-5256.2018.06.020
详细信息
  • 中图分类号: R459.3;R656

Clinical effect and safety of nutritional support after pancreaticoduodenectomy: A Meta-analysis

  • 摘要: 目的评估各种不同术后营养方式(包括全肠外营养、早期口服营养、鼻空肠管早期肠内营养、胃造瘘管早期肠内营养及空肠造瘘管早期肠内营养)对胰十二指肠切除(PD)术后患者预后的影响。方法检索Pubmed、Embase、Cochrane Library中PD术后营养支持相关文献,检索时间为2007年-2017年。将文献中研究对象及样本量、术式及术后营养方式、住院时间、感染(包括术后肺部感染、切口感染)发生率、胰瘘(B/C级)发生率、胃排空障碍的发生率纳入采用汇总分析,并采用Rev Man5.3软件对术后全肠外营养与鼻空肠管早期肠内营养情况进行Meta分析。结果最终纳入11篇文献,4篇文献行Meta分析。横向比较发现不同营养途径支持的患者的住院天数无明显规律,纵向比较发现不同研究相同营养给予方式下患者的住院天数差异较大。在并发症方面,胃造瘘组的胰瘘发生率明显高于其他组(P值均<0.01);空肠造瘘组的胃排空延迟障碍发生率均高于其他组(P值均<0.01)。全肠外营养感染发生率为27.17%,低于口服营养组之外的其他组(40.63%、46.58%、33.64%),但差异无统计学意义(P值均&...

     

  • [1]MARIN FA, LAMONICA VC, HENRY MA, et al.Grade of esophageal cancer and nutritional status impact on postsurgery outcomes[J].Arq Gastroenterol, 2010, 47 (4) :348-353.
    [2]DONG K, YU XJ, LI B, et al.Advances in mechanisms of postsurgical gastroparesis syndrome and its diagnosis and treatment[J].Chin J Dig Dis, 2006, 7 (2) :76-82.
    [3]CORREIA MI, WAITZBERG DL.The impact of malnutrition on morbidity, mortality, length of hospital stay and costs evaluated through a multivariate model analysis[J].Clin Nutr, 2003, 22 (3) :235-239.
    [4]MAZAKI T, EBISAWA K.Enteral versus parenteral nutrition after gastrointestinal surgery:A systematic review and metaanalysis of randomized controlled trials in the English literature[J].Gastrointest Surg, 2008, 12 (4) :739-755.
    [5]GERRITSEN A, BESSELINK MGH, GOUMA DJ, et al.Systematic review of five feeding routes after Pancreatoduodenectomy[J].Br J Surg, 2013, 100 (5) :589-598.
    [6]MOHER D, LIBERATI A, TETZLAFF J, et al (PRISMA Group) .Preferred reporting items for systematic reviews and meta-analyses:The PRISMA statement[J].Ann Intern Med, 2009, 151 (62) :264-269.
    [7]CEBM.Oxford Centre for Evidence-Based Medicine Levels of Evidence Working Group[EB/OL].OCEBM Levels of Evidence, 2011.http://www.cebm.net/index.aspx?o=5653.
    [8]WENTE MN, BASSI C, DERVENIS C, et al.Delayed gastric emptying (DGE) after pancreatic surgery:A suggested definition by the International Study Group of Pancreatic Surgery (ISGPS) [J].Surgery, 2007, 142 (5) :761-768.
    [9]BASSI C, DERVENIS C, BUTTURINI G, et al.Postoperative pancreatic fistula:An international study group (ISGPF) definition[J].Surgery, 2005, 138 (1) :8-13.
    [10]BERBERAT PO, INGOLD H, GULBINAS A, et al.Fast track-different implications in pancreatic surgery[J].Gastrointest Surg, 2007, 11 (7) :880-887.
    [11]RAYS N, SEEHOFER D, THERUVATH T, et al.Effect of enteral nutrition and synbiotics on bacterial infection rates after pyloruspreserving pancreatoduodenectomy:A randomized, double-blind trial[J].Ann Surg, 2007, 246 (1) :36-41.
    [12]BALZANO G, ZERBI A, BRAGA M, et al.Fast-track recovery programme after pancreaticoduodenectomy reduces delayed gastric emptying[J].Br J Surg, 2008, 95 (11) :1387-1393.
    [13]HALLAY J, MICSKER C, FULESDI B, et al.Use of three lumen catheter facilitates bowelmovement after pancreato-duodenectomy[J].Hepatogastroenterology, 2008, 55 (84) :1099-1102.
    [14]YERMILOV I, JAIN S, SEKERIS E, et al.Utilization of parenteral nutrition following pancreaticoduodenectomy:Is routine jejunostomy tube placement warranted?[J].Dig Dis Sci, 2009, 54 (7) :1582-1588.
    [15]ABU-HILAL M, HEMANDAS AK, Mc PHAIL M, et al.A comparative analysis of safety and efficacy of different methods of tube placement for enteral feeding following major pancreatic resection.A non-randomized study[J].JOP, 2010, 11 (1) :8-13.
    [16]GERRITSEN A, BESSELINK MG, CIESLAK KP, et al.Efficacy and complications of nasojejunal, jejunostomy and parenteral feeding after pancreaticoduodenectomy[J].J Gastrointest Surg, 2012, 16 (6) :1144-1151.
    [17]PARK JS, CHUNG HK, HWANG HK, et al.Postoperative nutritional effects of early enteral feeding compared with total parental nutrition in pancreaticoduodectomy patients:A prosepective, randomized study[J].Korean Med Sci, 2012, 27 (3) :261-267.
    [18]ZHU XH, WU YF, QIU DY, et al.Effect of early enteral combined with parenteral nutrition in patients undergoing pancreaticoduodenectomy[J].World J Gastroenterol, 2013, 19 (35) :5889-5896.
    [19]LU JW, LIU C, DU ZQ, et al.Early enteral nutrition vs parenteral nutrition following pancreaticoduodenectomy:Experience from a single center[J].World J Gastroenterol, 2016, 22 (14) :3821-3828.
    [20]GUILBAUD T, BIRNBAUM DJ, LOUBIRE S, et al.Comparison of different feeding regimes after pancreatoduodenectomy-a retrospective cohort analysis[J].Nutr J, 2017, 16 (1) :42.
    [21]BRAUNSCHWEIG CL, LEVY P, SHEEAN PM, et al.Enteral compared with parenteral nutrition:A meta-analysis[J].Am J Clin Nutr, 2001, 74 (4) :534-542.
    [22]MAHADEVA S, MALIK A, HILMI I, et al.Transnasal endoscopic placement of nasoenteric feeding tubes:Outcomes and limitations in non-critically ill patients[J].Nutr Clin Pract, 2008, 23 (2) :176-181.
  • 加载中
计量
  • 文章访问数:  1633
  • HTML全文浏览量:  10
  • PDF下载量:  342
  • 被引次数: 0
出版历程
  • 收稿日期:  2017-11-02
  • 出版日期:  2018-06-20
  • 分享
  • 用微信扫码二维码

    分享至好友和朋友圈

目录

    /

    返回文章
    返回