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Distribution features of TCM syndrome types and syndrome elements of primary biliary cholangitis:a literature review
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摘要:
目的通过文献研究,探索原发性胆汁性胆管炎(PBC)证候类型及证候要素分布规律,为探索PBC证候内涵和规律提供依据。方法计算机系统检索中国学术期刊全文数据库(CNKI)、中国生物医学文献数据库(CBM)、重庆维普中文期刊数据库(CQVIP)、万方数据库以及外文生物医学文献数据库(Pub Med)建库至2017年8月31日PBC有关文献,采用Note Express2.0软件进行PBC证候文献筛选,应用统计软件SPSS19.0进行统计分析。结果最终纳入文献11篇,报道病例总数849例,经规范后PBC证型19种,与PBC相关的证候要素18个。从证候出现频次以及病例构成比两个角度进行统计分析,得到PBC核心证候类型依次为:肝肾阴虚证、肝郁脾虚证;病位证素主要为:肝、脾、肾;病性证素主要为:气虚、湿、阴虚、气滞、血瘀、热。临床症状期证型主要为:肝郁脾虚证、肝肾阴虚证、脾胃气虚证,病位证素主要为:肝、脾,病性证素主要为:气虚、气滞、阴虚、湿阻。肝硬化失代偿期证型主要为:肝肾阴虚证、肝肾亏虚证、湿阻血瘀证,而病位证素主要为:肝、肾,病性证素主要为:阴虚、湿阻、血瘀、精亏。结论初步概括了PBC常见证型...
Abstract:Objective To investigate the distribution features of traditional Chinese medicine (TCM) syndromes types and syndrome elements of primary biliary cholangitis (PBC) via literature research, and to provide a basis for further research on PBC syndromes and features.Methods CNKI, CBM, CQVIP, Wanfang Data, and Pub Med were searched for articles on PBC published up to August 31, 2017.Note Express2.0 was used for the screening of articles on PBC syndromes, and SPSS19.0 was used for statistical analysis.Results A total of 11 articles with 849 cases were included, and 19 PBC syndrome types and 18 syndrome elements were identified.A statistical analysis was performed from the aspects of the frequency of syndromes and the constituent ratio of cases, and the results showed that the core syndrome types of PBC were liver-kidney yin deficiency syndrome and the syndrome of stagnation of liver qi and spleen deficiency; major syndrome elements of disease location were the liver, the spleen, and the kidney; major syndrome elements reflecting the nature of disease included qi deficiency, dampness, yin deficiency, qi stagnation, blood stasis, and heat.Major syndrome types in the clinical symptom stage included stagnation of liver qi and spleen deficiency, liver-kidney yin deficiency, and deficiency of spleen qi and stomach qi, and major syndrome elements reflecting the nature of disease included qi deficiency, qi stagnation, yin deficiency, and dampness.Major syndrome types of decompensated cirrhosis included liver-kidney yin deficiency, deficiency of liver and kidney, and dampness and blood stasis; major syndrome elements of disease location were the liver and the kidney; major syndrome elements reflecting the nature of disease included yin deficiency, dampness, blood stasis, and deficiency of essence.Conclusion Distribution features of common syndrome types and syndrome elements of PBC summarized in this article lay a foundation for the development of the standards for TCM syndrome differentiation of PBC.
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Key words:
- primary biliary cholangitis /
- symptom complex /
- review literature as topic
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[1]Chinese Society of Hepatology, Chinese Medical Association;Chinese Society of Gastroenterology, Chinese Medical Association;Chinese Society of Infectious Diseases, Chinese Medical Association.Consensus on the diagnosis and management of primary biliary cirrhosis (cholangitis) (2015) [J].J Clin Hepatol, 2015, 31 (12) :1980-1988. (in Chinese) 中华医学会肝病学分会, 中华医学会消化病学分会, 中华医学会感染病学分会.原发性胆汁性肝硬化 (又名原发性胆汁性胆管炎) 诊断和治疗共识 (2015) [J].临床肝胆病杂志, 2015, 31 (12) :1980-1988. [2]WANG L, GERSHWIN ME, WANG FS.Primary biliary cholangitis in China[J].Curr Opin Gastroenterol, 2016, 32 (3) :195-203. [3]CAREY EJ, ALI AH, LINDOR KD.Primary biliary cirrhosis[J].Lancet, 2015, 386 (10003) :1565-1575. [4]FAN XQ, WANG CS, LIU JT, et al.Clinical treatment progress of ursodeoxycholic acid in primary biliary cirrhosis[J].China Med Herald, 2016, 13 (24) :58-61. (in Chinese) 樊雪强, 王彩生, 刘金涛, 等.熊去氧胆酸在原发性胆汁性肝硬化临床治疗中的进展[J].中国医药导报, 2016, 13 (24) :58-61. [5]LI HY, XUE BY.Chinese medicine regularity on primary biliary cirrhosis in last ten years[J].Chin J Exp Tradit Med Form, 2014, 20 (3) :209-213. (in Chinese) 李红玉, 薛博瑜.原发性胆汁性肝硬化中医证治用药规律的文献研究[J].中国实验方剂学杂志, 2014, 20 (3) :209-213. [6] State Bureau of Technical Supervision.National standards of People's Republic of China:Clinical diagnosis and treatment term of TCM&syndrome part:GB/T16751.2-1997[S].Beijing:Standards Press of China, 1997. (in Chinese) 国家技术监督局.中华人民共和国国家标准:中医临床诊疗术语 (证候部分) :GB/T16751.2-1997[S].北京:中国标准出版社, 1997. [7]LI CD, WU CY.Diagnostics of traditional Chinese Medicine[M].3rd Edication.Beijing:China Press of Traditional Chinese Medicine, 2012:1-233. (in Chinese) 李灿东, 吴承玉.中医诊断学[M].3版.北京:中国中医药出版社, 2012:1-233. [8]YAO NL.Differential diagnosis of TCM syndrome[M].2nd Edition.Beijing:People's Medical Publishing House, 2002:122-455. (in Chinese) 姚乃礼.中医证候鉴别诊断学[M].2版.北京:人民卫生出版社, 2002:122-455. [9]DONG ZH, XU HY, QI HB.Study on the law of syndrome differentiation of primary biliary cirrhosis by traditional chinese medicine:a74-case report[J].J Med Res, 2011, 40 (5) :83-85. (in Chinese) 董振华, 徐慧媛, 齐贺彬.原发性胆汁性肝硬化74例中医辨证规律的研究[J].医学研究杂志, 2011, 40 (5) :83-85 [10]CHENG LB, WU F.The clinical analysis of TCM on primary biliary cirrhosis[J].Hubei J Tradit Chin Med, 2011, 33 (2) :13-14. (in Chinese) 程良斌, 吴凡.原发性胆汁性肝硬化中医临床分析[J].湖北中医杂志, 2011, 33 (2) :13-14. [11] LI QM.Clinical features of traditional Chinese medicine and Western medicine in patients with primary biliary cirrhosis[D].Shanghai:Shanghai Univ Chin Med, 2012. (in Chinese) 李青梅.原发性胆汁性肝硬化患者中西医临床特征分析[D].上海:上海中医药大学, 2012. [12]LU DQ.The feature research of traditional Chinese medicine syndrome of primary biliary cirrhosis[D].Nanjing:Nanjing Univ Chin Med, 2012. (in Chinese) 卢殿强.原发性胆汁性肝硬化的中医证候分布特点研究[D].南京:南京中医药大学, 2012. [13]CAO XB.Clinical effect observation of traditional Chinese medicine clinical of primary biliary cirrhosis[J].Chin J Clin Ration Drug Use, 2013, 6 (13) :31-32. (in Chinese) 曹学斌.中医药治疗原发性胆汁性肝硬化临床疗效观察[J].临床合理用药杂志, 2013, 6 (13) :31-32. [14] WANG SG.The clinical analysis of TCM on primary biliary cirrhosis[J].Med Inf, 2014, 27 (9) :410. (in Chinese) 王书光.原发性胆汁性肝硬化中医治疗临床分析[J].医学信息, 2014, 27 (9) :410. [15]YANG JL, ZHANG MZ, ZHANG B.The analysis of TCM syndrome and clinical features for 74 cases patients with primary biliary cirrhosis[J].Chin J Integr Tradit West Med Liver Dis, 2015, 25 (4) :209-211. (in Chinese) 杨将领, 张美珠, 张斌.74例原发性胆汁性肝硬化患者中医证型及临床特征分析[J].中西医结合肝病杂志, 2015, 25 (4) :209-211. [16]LI LX.The research on traditional Chinese medicine syndrome characteristic of primary biliary cirrhosis patients and the mechanism of Tiaogan Lipi Decotion[D].Taiyuan:Shanxi Institute Tradit Chin Med, 2015. (in Chinese) 李良学.原发性胆汁性肝硬化中医证候特点和调肝理脾方作用机理研究[D].太原:山西省中医药研究院, 2015. [17]MA Y.Study on TCM syndrome of primary biliary cirrhosis[C]//China J Chin Mater Med 2015/Special Collection:Collection of papers on scientific paper writing training conference to Practitioners of Basic Medical Institutions, 2016. (in Chinese) 马燕.原发性胆汁性肝硬化的中医证候研究[C]//中国中药杂志2015/专集:基层医疗机构从业人员科技论文写作培训会议论文集, 2016. [18]JIANG L, WANG D, HUANG XM.Discriminant analysis of TCM syndrome in primary biliary cirrhosis[J].Zhejiang Clin Med J, 2017, 19 (8) :1576-1577. (in Chinese) 蒋镥, 王丹, 黄小民.原发性胆汁性肝硬化中医证型的判别分析原发性胆汁性肝硬化中医证型的判别分析[J].浙江临床医学, 2017, 19 (8) :1576-1577. [19]DU HB, JIANG YY, XUE YC, et al.Survey on Chinese medicine syndrome of 96 patients with primary biliary cirrhosis[J].J Tradit Chin Med, 2017, 58 (7) :575-578. (in Chinese) 杜宏波, 江宇泳, 薛亚春, 等.96例原发性胆汁性肝硬化患者中医证候调查[J].中医杂志, 2017, 58 (7) :575-578. [20]WANG LF, LI YY, JIN L, et al.Epidemiology and natural history of primary biliary cirrhosis[J].J Clin Hepatol, 2015, 31 (2) :165-170. (in Chinese) 王立峰, 李元元, 金磊, 等.原发性胆汁性肝硬化的流行病学与自然史变迁[J].临床肝胆病杂志, 2015, 31 (2) :165-170. [21]ZHU WF.Meaning of establishing new system of“differentiation by sign factors”[J].J Zhejiang Univ Tradit Chin Med, 2006, 30 (2) :135-136, 142. (in Chinese) 朱文锋.构建“证素辨证”新体系的意义[J].浙江中医药大学学报, 2006, 30 (2) :135-136, 142. -
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