尾状叶肝细胞癌非切除性局部治疗的现状及进展

姚常玉; 杜英瑞; 柯山; 高君; 孙文兵

doi:10.3969/j.issn.1001-5256.2018.01.043

尾状叶肝细胞癌非切除性局部治疗的现状及进展

DOI: 10.3969/j.issn.1001-5256.2018.01.043

首都医科大学附属北京朝阳医院西区肝胆胰脾外科

基金项目:

国家自然科学基金(81572957,81502650)；吴阶平医学基金(320675015275)；

详细信息

中图分类号: R735.7
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出版历程
- 出版日期: 2018-01-20

Current status of non-surgical local therapies for hepatocellular carcinoma originating from the caudate lobe and related research advances

Department of Hepatobiliary-Pancreatic-Splenic Surgery, West Branch of Beijing Chaoyang Hospital, Capital Medical University, Beijing 100043, China

Research funding:

摘要

摘要:
尾状叶肝细胞癌是一种特殊部位的肝细胞癌,手术切除是其传统治疗手段。但是,由于尾状叶解剖位置特殊及其结构复杂,手术切除特别是腹腔镜下切除,常有困难。近十年来,射频消融、微波消融、经肝动脉化疗栓塞术、无水酒精注射、放射治疗等非手术局部治疗方法在尾状叶肝细胞癌的综合治疗中发挥了越来越重要的作用,成为了许多不适合手术切除尾状叶肝细胞癌患者的首选治疗方式。针对尾状叶肝细胞癌的非手术局部治疗方法的现状及进展进行了讨论。
- 癌,肝细胞 /
- 治疗 /
- 综述
Abstract:
Hepatocellular carcinoma originating from the caudate lobe is a special type of hepatocellular carcinoma, and surgical resection is a conventional therapeutic method for this disease. However, the special anatomical position and complex structure of the caudate lobe make it difficult to perform surgical resection, especially laparoscopic resection. In the past decade, non-surgical local therapies, such as radiofrequency ablation, microwave ablation, transcatheter arterial chemoembolization, ethanol injection, and radiotherapy, are playing a more and more important role in the comprehensive treatment of hepatocellular carcinoma originating from the caudate lobe and have been recommended as the preferred treatment modality for patients with such disease who are not suitable for surgical resection. This article discusses the current status of non-surgical local therapies for hepatocellular carcinoma originating from the caudate lobe and related research advances.
- carcinoma, hepatocellular /
- therapy /
- review

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参考文献(33)

[1]TAKAYASU K, MURAMATSU Y, SHIMA Y, et al.Clinical and radiologic features of hepatocellular carcinoma originating in the caudate lobe[J].Cancer, 1986, 58 (7) :1557-1562.

[2]AHANATHA PILLAI S, SATHYANESAN J, PERUMAL S, et al.Isolated caudate lobe resection:technical challenges[J].Ann Gastroenterol, 2013, 26 (2) :150-155.

[3]ZENG DB, DI L, GAO DM, et al.A case of total laparoscopic hepatectomy for primary liver cancer originating from the caudate lobe[J].Chin J Hepatobiliary Surg, 2016, 22 (1) :32, 61. (in Chinese) 曾道炳, 邸亮, 高大明, 等.完全腹腔镜下肝尾状叶原发性肝癌切除术一例[J].中华肝胆外科杂志, 2016, 22 (1) :32, 61.

[4]CHEN HW, DENG FW, WANG FJ, et al.Laparoscopic hepatic caudate lobe resection:a report of 7 patients[J].Chin J Hepatobiliary Surg, 2017, 23 (5) :304-306. (in Chinese) 陈焕伟, 邓斐文, 王峰杰, 等.腹腔镜肝尾状叶切除术七例报告[J].中华肝胆外科杂志, 2017, 23 (5) :304-306.

[5]YANG Y, ZHANG YC.Thoughts on future directions of liver transplantation for liver cancer[J].Ogran Transplantation, 2016, 7 (1) :1-7. (in Chinese) 杨扬, 张英才.肝癌肝移植未来方向的思考[J].器官移植, 2016, 7 (1) :1-7.

[6]WANG HM.The interventional treatment for hepatocellular carcinoma originating from the caudate lobe[J].J Clin Hepatol, 2016, 32 (1) :68-71. (in Chinese) 王华明.尾状叶肝癌的介入治疗[J].临床肝胆病杂志, 2016, 32 (1) :68-71.

[7]WANG XA, LIU YB, QUAN ZW, et al.Importance of surgical anatomy in the resection of caudate lobe[J].Chin J Pract Surg, 2014, 34 (8) :720-723. (in Chinese) 王许安, 刘颖斌, 全志伟, 等.临床解剖结构在肝尾状叶切除术中的重要性[J].中国实用外科杂志, 2014, 34 (8) :720-723.

[8]HORIE Y, SHIGOKU A, TANAKA H, et al.Prognosis for pedunculated hepatocellular carcinoma[J].Oncology, 1999, 57 (1) :23-28.

[9] SUN WB.The importance of pathological complete ablation on the efficacy of radiofrequency ablation in liver cancer[J].Chin J Hepatobiliary Surg, 2011, 17 (3) :182-185. (in Chinese) 孙文兵.重视病理性完全消融提高肝癌射频消融疗效[J].中华肝胆外科杂志, 2011, 17 (3) :182-185.

[10]LIVRAGHI T, MELONI F, DI STASI M, et al.Sustained complete response and complications rates after radiofrequency ablation of very early hepatocellular carcinoma in cirrhosis:Is resection still the treatment of choice?[J].Hepatology, 2008, 47 (1) :82-89.

[11]CHA CH, LEE FT Jr, GURNEY JM, et al.CT versus sonography for monitoring radiofrequency ablation in a porcine liver[J].AJR Am J Roentgenol, 2000, 175 (3) :705-711.

[12]JIANG K, ZHANG W, SU M, et al.Laparoscopic radiofrequency ablation of solitary small hepatocellular carcinoma in the caudate lobe[J].Eur J Surg Oncol, 2013, 39 (11) :1236-1242.

[13]ISHIKO T, BEPPU T, SUGIYAMA S, et al.Radiofrequency ablation with hand-assisted laparoscopic surgery for the treatment of hepatocellular carcinoma in the caudate lobe[J].Surg Laparosc Endosc Percutan Tech, 2008, 18 (3) :272-276.

[14]NISHIGAKI Y, TOMITA E, HAYASHI H, et al.Efficacy and safety of radiofrequency ablation for hepatocellular carcinoma in the caudate lobe of the liver[J].Hepatol Res, 2013, 43 (5) :467-474.

[15]DONG J, LI W, ZENG Q, et al.CT-guided percutaneous stepby-step radiofrequency ablation for the treatment of carcinoma in the caudate lobe[J].Medicine (Baltimore) , 2015, 94 (39) :e1594.

[16]HIROOKA M, KISAKA Y, UESUGI K, et al.Virtual puncture line in radiofrequency ablation for hepatocellular carcinoma of the caudate lobe[J].AJR Am J Roentgenol, 2009, 193 (2) :w149-w151.

[17]PENG ZW, LIANG HH, CHEN MS, et al.Percutaneous radiofrequency ablation for the treatment of hepatocellular carcinoma in the caudate lobe[J].Eur J Surg Oncol, 2008, 34 (2) :166-172.

[18]KARIYAMA K, NOUSO K, WAKUTA A, et al.Percutaneous radiofrequency ablation for treatment of hepatocellular carcinoma in the caudate lobe[J].AJR Am J Roentgenol, 2011, 197 (4) :w571-w575.

[19]ZHANG Y, LI YF, ZHAO W.Microwave ablation for treatment of hepatocellular carcinoma originating from the caudate lobe:a report of one case[J].Chin Hepatol, 2010, 15 (6) :413. (in Chinese) 张毅, 李一凡, 赵炜.微波消融术治疗尾状叶肝癌1例[J].肝脏, 2010, 15 (6) :413.

[20]WU JX.Open microwave ablation for the treatment of caudate lobe tumor:a report of three cases[J].Mod Med Health, 2016, 32 (17) :2778-2779. (in Chinese) 吴嘉兴.开腹微波消融治疗尾状叶肿瘤3例[J].现代医药卫生, 2016, 32 (17) :2778-2779.

[21]ZHU JJ, GE NJ, LIU X, et al.Short-term local efficacy of radiofrequency ablation in treatment of hepatocellular carcinoma in the caudate lobe[J].J Hepatobiliary Surg, 2015, 23 (5) :382-383. (in Chinese) 朱俊军, 葛乃建, 刘学, 等.尾状叶肝癌射频消融的局部疗效的短期观察[J].肝胆外科杂志, 2015, 23 (5) :382-383.

[22]DOU JP, YU J, CHENG ZG, et al.Ultrasound-guided percutaneous microwave ablation for hepatocellular aarcinoma in the caudate lobe[J].Ultrasound Med Biol, 2016, 42 (8) :1825-1833.

[23]WU XS, LI ML, WU WG, et al.The role of preoperative TACE on hepatocellular carcinoma located in caudate lobe[J].Chin J Surg, 2013, 51 (9) :780-783. (in Chinese) 吴向嵩, 李茂岚, 吴文广, 等.术前经动脉栓塞化疗治疗尾状叶肝细胞癌[J].中华外科杂志, 2013, 51 (9) :780-783.

[24]KIM HC, CHUNG JW, JAE HJ, et al.Caudate lobe hepatocellular carcinoma treated with selective chemoembolization[J].Radiology, 2010, 257 (1) :278-287.

[25]SHIBATA T, MAETANI Y, AMETANI F, et al.Efficacy of nonsurgical treatments for hepatocellular carcinoma in the caudate lobe[J].Cardiovasc Intervent Radiol, 2002, 25 (3) :186-192.

[26]XU ZF, XIE XY, CUI Y, et al.Initial clinical experience of ethanol ablation with endoscopic ultrasonography guidance for 10 cases of hepatocellular carcinoma which are difficult to reach by percutaneous mode[J/CD].Chin J Med Ultrasound:Electronic Edition, 2011, 8 (9) :1964-1969. (in Chinese) 徐作峰, 谢晓燕, 崔毅, 等.超声内镜引导无水酒精治疗特殊部位肝癌10例[J/CD].中华医学超声杂志:电子版, 2011, 8 (9) :1964-1969.

[27]SHAO L, KONG X, SHI YX, et al.Gamma stereotactic radiotherapy for early primary liver cancer[J].Trauma Critic Care Med, 2017, 5 (1) :36-38. (in Chinese) 邵亮, 孔欣, 施艳新, 等.伽玛射线立体定向放射治疗早期原发性肝癌临床研究[J].创伤与急危重病医学, 2017, 5 (1) :36-38.

[28]LIN YH, HUNG SK, CHIOU WY, et al.Significant symptoms alleviation and tumor volume reduction after combined simultaneously integrated inner-escalated boost and volumetric-modulated arc radiotherapy in a patient with unresectable bulky hepatocellular carcinoma:a care-compliant case report[J].Medicine (Baltimore) , 2016, 95 (34) :e4717.

[29]JACOB R, TURLEY F, REDDEN DT, et al.Adjuvant stereotactic body radiotherapy following transarterial chemoembolization in patients with non-resectable hepatocellular carcinoma tumours of≥3cm[J].HPB (Oxford) , 2015, 17 (2) :140-149.

[30]SANGRO B, INARRAIRAEGUI M, BILBAO JI.Radioembolization for hepatocellular carcinoma[J].J Hepatol, 2012, 56 (2) :464-473.

[31]IBRAHIM SM, KULIK L, BAKER T, et al.Treating and downstaging hepatocellular carcinoma in the caudate lobe with yttrium-90 radioembolization[J].Cardiovasc Intervent Radiol, 2012, 35 (5) :1094-1101.

[32]SU BB, GAO YZ, LI Z, et al.CT-guided radiofrequency ablation of caudate lobe of liver cancer[J].J Aerospace Med, 2014, 25 (10) :1337-1338. (in Chinese) 宿贝贝, 高原智, 李真, 等.CT引导下肝尾叶肝癌的射频消融治疗[J].航空航天医学杂志, 2014, 25 (10) :1337-1338.

[33]HYUN D, CHO SK, SHIN SW, et al.Treatment of small hepatocellular carcinoma (≤2 cm) in the caudate lobe with sequential transcatheter arterial chemoembolization and radiofrequency ablation[J].Cardiovasc Intervent Radiol, 2016, 39 (7) :1015-1022.

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