药物性肝损伤1例报告及治疗体会

任艳; 郑素军

doi:10.3969/j.issn.1001-5256.2017.12.029

药物性肝损伤1例报告及治疗体会

DOI: 10.3969/j.issn.1001-5256.2017.12.029

任艳,
郑素军

首都医科大学附属北京佑安医院疑难肝病及人工肝中心

详细信息

中图分类号: R575
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- 被引次数: 0
出版历程
- 出版日期: 2017-12-20

Experience in clinical treatment of drug-induced liver injury:a case report

Artificial Liver Treatment & Training Center, Beijing YouAn Hospital

摘要

摘要: <正>药物诱导的肝损伤所涉及的药物范围广泛,临床表现类型多变,且缺乏特异性的诊断标志物,使药物性肝损伤的诊断及管理变得尤为困难。现将本院收治的1例药物性肝损伤及治疗体会报告如下。1病例资料患者女性,86岁,因"尿黄1周"于2016年10月26日以"肝功能异常"收入本院疑难肝病及人工肝中心。1周前患者自觉小便颜色加深,无纳差、乏力、恶心、呕吐、腹胀等不适,大便颜色正常。查体:生命体征平稳,神志清,精神可,皮肤及巩
- 肝炎,中毒性 /
- 治疗 /
- 病例报告
- hepatitis, toxic /
- therapy /
- case reports

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参考文献(9)

[1]Drug-induced Liver Disease Study Group, Chinese Society of Hepatology, Chinese Medical Association.Guidelines for the management of drug-induced liver injury[J].J Clin Hepatol, 2015, 31 (11) :1752-1769. (in Chinese) 中华医学会肝病学分会药物性肝病学组.药物性肝损伤诊治指南[J].临床肝胆病杂志, 2015, 31 (11) :1752-1769.

[2]LIU LN, CHEN W, GUO HY, et al.Comparative study on clinical characteristics of 78 cases with drug-induced liver injury caused by traditional Chinese medicine or Western medicine[J/CD].Chin JLiver Dis:Electronic Edition, 2015, 7 (1) :46-50. (in Chinese) 刘丽娜, 陈婉, 郭海燕, 等.78例中药与西药引发药物性肝损伤的临床特性研究[J/CD].中国肝脏病杂志:电子版, 2015, 7 (1) :46-50.

[3]CHALASANI NP, HAYASHI PH, BONKOVSKY HL, et al.ACGClinical Guideline:the diagnosis and management of idiosyncratic drug-induced liver injury[J].Am J Gastroenterol, 2014, 109 (7) :950-966, 967.

[4]XU ZL, GAO M, GUO CX, et al.Clinical features of different types of drug-induced liver injury and their association with liver histological changes[J].J Clin Hepatol, 2017, 33 (5) :924-927. (in Chinese) 徐曾丽, 高敏, 郭春霞, 等.药物性肝损伤临床分型特点及其与肝组织学改变的关系[J].临床肝胆病杂志, 2017, 33 (5) :924-927.

[5]HAN P, TIAN DA.New progress of pathogenesis and therapeutic agents of hepatic cholestasis[J].Chin J Gastroenterol Hepatol, 2016, 25 (5) :584-588. (in Chinese) 韩平, 田德安.肝内胆汁淤积发病机制及药物治疗新进展[J].胃肠病学和肝病学杂志, 2016, 25 (5) :584-588.

[6]HU Q, LIU W, SHAO H.Research progress of pharmacotherapy drug-induced liver injury[J].Chin J Clin Pharmacol Ther, 2016, 21 (2) :231-236. (in Chinese) 胡琴, 刘维, 邵宏.药物性肝损伤的药物治疗研究进展[J].中国临床药理学与治疗学, 2016, 21 (2) :231-236.

[7]HU L.Clinical effect of low-molecular-weight heparin in treatment of intrahepatic cholestasis of pregnancy:an analysis of 76 cases[J].China Prac Med, 2014, 9 (6) :181. (in Chinese) 胡莉.低分子肝素治疗妊娠期肝内胆汁淤积症76例疗效观察[J].中国实用医药, 2014, 9 (6) :181.

[8]HAO JH, SHI J, REN WH, et al.The usage of heparin in the treatment of patients with chronic hepatitis B[J].J Clin Hepatol, 2002, 18 (2) :109-110. (in Chinese) 郝菁华, 石军, 任万华, 等.肝素在慢性乙型肝炎治疗中的应用[J].临床肝胆病杂志, 2002, 18 (2) :109-110.

[9]HAO JH, SHI J, REN WH, et al.Clinical studies on imoprovement of hepatic microcirculation in patients with chronic hepatitis B[J].Chin J Microcirc, 2001, 11 (4) :9-11. (in Chinese) 郝菁华, 石军, 任万华, 等.肝素改善慢性乙型肝炎患者肝脏微循环的临床研究[J].微循环学杂志, 2001, 11 (4) :9-11.

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