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射波刀治疗复发性肝癌患者的效果及预后分析

李欢 孙静 张弢 范毓泽 孙颖哲 何卫平 段学章

引用本文:
Citation:

射波刀治疗复发性肝癌患者的效果及预后分析

DOI: 10.3969/j.issn.1001-5256.2017.12.016
基金项目: 

基金项目:北京市海淀区预防医学会(2016HDPMA09); 

详细信息
  • 中图分类号: R735.7

Effect of Cyber Knife radiosurgery on survival rate of patients with recurrent liver cancer after surgery

Research funding: 

 

  • 摘要: 目的分析射波刀立体定向放射治疗切除术后、消融术后复发性肝癌的效果和影响生存率的相关因素。方法对2011年1月-2014年1月于中国人民解放军三○二医院行射波刀治疗的34例术后复发性肝癌患者进行回顾性分析,计算患者放疗后的生存率和生存时间,分析影响其生存的相关因素。肿瘤靶区(GTV)为1.4751082.075 cm3,中位值162.99 cm3,分割剂量720 Gy/次(中位值9 Gy),照射次数28次(中位值5次),肿瘤剂量2460 Gy(中位值45 Gy),每日照射1次。主要观察指标为近期疗效、毒副作用、远期疗效。Log-rank检验分析生存相关影响因素,计数资料组间比较采用χ2检验和Fisher精确检验。结果放疗后患者1、2、3年总体生存率分别为91.2%、70.6%和44.1%,中位生存期34个月。1、2、3年的无进展生存率分别为55.9%、38.2%、29.4%。术后≤1年(早期)及>1年(晚期)复发组经放疗后1、2、3年总体生存率分别为89%、73.7%、57.9%和93%、73....

     

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  • 收稿日期:  2017-06-13
  • 出版日期:  2017-12-20
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