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影像学在非酒精性脂肪性肝病临床研究及实践中的地位

王屹

引用本文:
Citation:

影像学在非酒精性脂肪性肝病临床研究及实践中的地位

DOI: 10.3969/j.issn.1001-5256.2017.12.010
详细信息
  • 中图分类号: R445;R575.5;R816.5

Role of imaging techniques in clinical research and practice on nonalcoholic fatty liver disease

  • 摘要: 腹部超声(US)、计算机断层扫描(CT)和磁共振影像(MRI)均被用于非酒精性脂肪性肝病(NAFLD)的临床诊断和研究中。阐述了US、CT、MRI评价NAFLD的优势与局限性。与传统影像学检查相比,多参数定量MRI技术能够客观全面地评价NAFLD。脂肪质子密度(PDFF)被认为是脂肪肝诊断金标准并被应用于临床研究中。PDFF的实用性、可靠性、可转化性在成人及儿童的独立临床研究中通过多个MR扫描系统及应用软件被反复证实。磁共振弹性成像能够评价肝纤维化程度,且不受肝脂肪变性的影响。NAFLD肝脂肪沉积及纤维化均可在MRI检查中一站式测定,并在一定程度上成为替代肝穿刺的诊断方法。

     

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  • 出版日期:  2017-12-20
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