胆源性胰腺炎术后复发的危险因素分析

李人立; 周庆

doi:10.3969/j.issn.1001-5256.2017.05.025

胆源性胰腺炎术后复发的危险因素分析

DOI: 10.3969/j.issn.1001-5256.2017.05.025

李人立,
周庆

1. 解放军第四医院外二科
2. 青海红十字医院胃肠外科

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中图分类号: R657.51
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出版历程
- 出版日期: 2017-05-20

Risk factors for recurrence after surgery for biliary pancreatitis

Li RenLi,
Zhou Qing

Second Department of General Surgery, The Fourth Hospital of PLA

摘要

摘要:
目的探讨胆源性胰腺炎术后复发的相关危险因素。方法选取解放军第四医院2008年1月-2014年12月收治的284例胆源性胰腺炎患者进行随访,对其术后复发的相关因素进行分析。计数资料组间比较采用χ2检验,进一步多因素分析采用非条件logistic回归分析法。结果随访时间672个月,平均（36.4±8.4）个月。27例患者术后复发,复发率为9.51%。单因素分析显示,术后复发与胆石症家族史、高脂饮食、泥沙样结石、合并肝内胆管结石、胆胰管开口狭窄、壶腹部周围憩室有关（χ2值分别为8.721、5.979、8.641、15.996、33.833、27.203,P值均<0.05）。logistic多因素分析显示高脂饮食[比值比（OR）=2.296,P=0.012]、胆胰管开口狭窄（OR=2.280,P=0.007）和壶腹部周围憩室（OR=2.522,P=0.009）是胆源性胰腺炎术后复发的独立危险因素。结论高脂饮食、合并胆胰腺管开口狭窄和壶腹部周围憩室的胆源性胰腺炎患者术后易复发,对于该类患者,要积极干预和密切随访,预防再次复发。
- 胰腺炎 /
- 胆道疾病 /
- 复发 /
- 因素分析,统计学
Abstract:
Objective To investigate the risk factors for recurrence after surgery for biliary pancreatitis.Methods A total of 284 patients with biliary pancreatitis who were treated in The Fourth Hospital of PLA from January 2008 to December 2014 were followed up, and the risk factors for postoperative recurrence were analyzed.The chi-square test was used for categorical data, and the unconditional logistic regression model was used for multivariate analysis.Results The follow-up period ranged from 6 to 27 months (mean 36.4 ± 8.4 months) .Of all patients, 27 experienced recurrence, and the recurrence rate was 9.51%.The univariate analysis showed that postoperative recurrence was associated with a family history of gallstone disease, high-fat diet, sand-like stones, intrahepatic bile duct stones, biliopancreatic duct opening stenosis, and diverticulum around the ampullar region (χ2=8.721, 5.979, 8.641, 15.996, 33.833, and 27.203, all P<0.05) .The multivariate logistic analysis showed that high-fat diet (OR=2.296, P=0.012) , biliopancreatic duct opening stenosis (OR=2.280, P=0.007) , and diverticulum around the ampullar region (OR=2.522, P=0.009) were independent risk factors for recurrence after surgery for biliary pancreatitis.Conclusion Biliary pancreatitis patients with high-fat diet, biliopancreatic duct opening stenosis, or diverticulum around the ampullar region tend to experience recurrence after surgery.Intervention and close follow-up should be performed for these patients to prevent recurrence.
- pancreatitis /
- biliary tract diseases /
- recurrence /
- factor analysis, statistical

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参考文献(14)

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