代谢综合征与胆囊结石的相关性分析

周冰冰; 王学梅; 张茜; 徐世燚; 单忠艳; 赖亚新; 王浩宇

doi:10.3969/j.issn.1001-5256.2017.05.017

代谢综合征与胆囊结石的相关性分析

DOI: 10.3969/j.issn.1001-5256.2017.05.017

1. 中国医科大学附属第一医院超声科
2. 中国医科大学附属第一医院内分泌科

基金项目:

“十二五”国家科技计划课题(2012BAI02B00)；

详细信息

中图分类号: R589;R575.62
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出版历程
- 出版日期: 2017-05-20

Association between metabolic syndrome and gallstones

Department of Ultrasound, The First Affiliated Hospital of China Medical University

Research funding:

摘要

摘要:
目的分析代谢综合征及其各个组分与胆囊结石发生的相关性,探讨影响胆囊结石患病率的相关因素。方法选取2015年1-6月中国医科大学附属第一医院内分泌科随访的社区人群445例为研究对象,将随访人群分为代谢综合征组220例和非代谢综合征组225例。对研究对象进行问卷调查、体格检查及血液检查,获取性别、年龄、身高、体质量、腰围、血压、血生化指标（空腹血糖、TG、HDL）等资料。计数资料2组间比较使用χ2检验,计量资料2组间比较使用t检验,并采用多因素logistic回归分析影响胆囊结石患病率的独立危险因素。结果总人群中胆囊结石患者共49例,占11.01%,其中代谢综合征组胆囊结石38例（17.27%）,非代谢综合征组胆囊结石11例（4.89%）,代谢综合征组胆囊结石的患病率显著增高（χ2=17.409,P<0.001）。多因素logistics回归分析显示胆囊结石的发生与腰围、TG、HDL独立相关[腰围:比值比（OR）=1.088,P<0.001;TG:OR=1.209,P=0.038;HDL:OR=0.329,P=0.014)。结论腰围增...
- 代谢综合征X /
- 胆囊结石病 /
- 危险因素
Abstract:
Objective To investigate the association of metabolic syndrome and its components with gallstones and the factors for the development of gallstones.Methods A total of 445 community residents, who were followed up by Department of Endocrinology in The First Affiliated Hospital of China Medical University from January to June, 2015, were enrolled as study subjects and were divided into metabolic syndrome group with 220 patients and non-metabolic syndrome group with 225 patients.A questionnaire survey, physical examination, and blood test were performed for these patients to obtain the data on sex, age, body height, body weight, waist circumference, blood pressure, and blood biochemical parameters[fasting blood glucose, triglyceride (TG) , and high-density lipoprotein (HDL) ].The chi-square test was used for comparison of categorical data between two groups, the t-test was used for comparison of continuous data between groups, and a multivariate logistic regression analysis was used to identify independent risk factors for the development of gallstones.Results Of all patients, 49 (11.01%) had gallstones, among whom 38 (17.27%) were in the metabolic syndrome group and 11 (4.89%) were in the non-metabolic syndrome group;the metabolic syndrome group had a significant increase in the prevalence rate of gallstones (χ2=17.409, P<0.001) .The multivariate logistic regression analysis showed that increased waist circumference (OR=1.088, P<0.001) , increased TG level (OR=1.209, P=0.038) , and reduced HDL level (OR=0.329, P=0.014) were independent risk factors for gallstones.Conclusion Increased waist circumference, increased TG level, and reduced HDL level may be independent risk factors for the development of gallstones.
- metabolic syndrome X /
- cholecystolithiasis /
- risk factors

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参考文献(15)

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