中文English
ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R

留言板

尊敬的读者、作者、审稿人, 关于本刊的投稿、审稿、编辑和出版的任何问题, 您可以本页添加留言。我们将尽快给您答复。谢谢您的支持!

姓名
邮箱
手机号码
标题
留言内容
验证码

胰性脑病的诊治现状

张永国 郭晓钟

引用本文:
Citation:

胰性脑病的诊治现状

DOI: 10.3969/j.issn.1001-5256.2017.01.009
详细信息
  • 中图分类号: R576;R747.9

Current status of diagnosis and treatment of pancreatic encephalopathy

  • 摘要: 胰性脑病(PE)是胰腺炎的严重并发症,早期诊断困难、预后差。介绍了胰酶激活、细胞因子、感染、水电解质紊乱、维生素缺乏等因素参与PE的可能发病机制。归纳了PE的临床表现和实验室检查特点,指出PE临床表现特异性不强,缺乏可靠的生化诊断指标,无明确的诊断标准。阐述了PE的诊治策略,指出PE的重点在于积极有效地治疗原发病,大部分PE患者随着胰腺炎病情的缓解而好转。

     

  • [1]ROTHERMICH NO,von HAAM E.Pancreatic encephalopathy[J].J Clin Endocr,1941,1(4):872-881.
    [2]ZHANG JP,NI JL.Research progress of pancreatic encephalopathy[J].J Hepatopancreatobiliary Surg,2011,23(5):439-440.(in Chinese)张建平,倪家连.胰性脑病诊治研究进展[J].肝胆胰外科杂志,2011,23(5):439-440.
    [3]WANG Q,LI X.Research progress of pancreatic encephalopathy in SAP[J].Chin J Pract Surg,2004,24(1):63-64.(in Chinese)汪谦,李湘.SAP病人胰性脑病的研究进展[J].中国实用外科杂志,2004,24(1):63-64.
    [4]MIAO Y,QIAN ZY.Diagnosis and treatment of pancreatic encephalopathy in SAP[J].J Hepatobiliary Surg,2005,13(1):6-8.(in Chinese)苗毅,钱祝银.重症急性胰腺炎胰性脑病的诊治[J].肝胆外科杂志,2005,13(1):6-8.
    [5]ZHANG XP,TIAN H.Pathogenesis of pancreatic encephalopathy in severe acute pancreatitis[J].Hepatobiliary Pancreat Dis Int,2007,6(2):134-140.
    [6]LIAO Z,LI ZS.Research progress of pancreatic encephalopathy[J].Chin J Pancreatol,2003,3(4):248-250.(in Chinese)廖专,李兆申.胰性脑病研究进展[J].中华胰腺病杂志,2003,3(4):248-250.
    [7]ZHANG XP,TIAN H.Pathogenesis of pancreatic encephalopathy in severe acute pancreatitis[J].World Chin J Digestol,2005,13(22):2667-2671.(in Chinese)张喜平,田华.重症急性胰腺炎并发胰性脑病的发病机制[J].世界华人消化杂志,2005,13(22):2667-2671.
    [8]KONG L.Pathogenesis and etiology of pancreatic encephalopathy[J].Chin J Curr Adv Gen Surg,2002,5(2):68-70.(in Chinese)孔雷.对胰性脑病病因和发病机制的认识[J].中国现代普通外科进展,2002,5(2):68-70.
    [9]XU Z,WANG CY.Research progresss of pancreatic encephalopathy about its mechanism,diagnosis and treatment[J].Med Recapitulate,2007,13(14):1087-1089.(in Chinese)许州,王春友.胰性脑病发病机制及诊治研究进展[J].医学综述,2007,13(14):1087-1089.
    [10]YIN BB,CAI D.Research progress of pancreatic encephalopathy[J].J Hepatopancreatobiliary Surg,2003,15(3):205-207.(in Chinese)殷保兵,蔡端.胰性脑病的诊治研究[J].肝胆胰外科杂志,2003,15(3):205-207.
    [11]LU CL.Current research on pancreatic encephalopathy[J].Chin J Gen Surg,2001,10(4):362-365.(in Chinese)卢崇亮.胰性脑病的研究现状[J].中国普通外科杂志,2001,10(4):362-365.
    [12]GUPTA R,DAS S,GUPTA R,et al.Altered sensorium in a chronic alcoholic:pancreatic encephalopathy,Wernicke's encephalopathy or Marchiafava Biganami disease?[J].Trop Gastroenterol,2015,36(4):266-268.
    [13]SUN B,XU J,ZHOU ZQ,et al.Diagnosis and treatment of pancreatic encephalopathy in severe acute pancreatitis[J].J Harbin Med Univ,2003,37(5):437-438.(in Chinese)孙备,许军,周尊强,等.重症急性胰腺炎并发胰性脑病的诊断与治疗[J].哈尔滨医科大学学报,2003,37(5):437-438.
    [14]CHEN LD,ZHANG XQ.Pancreatic encephalopathy and Wernicke's encephalopathy[J].Chin J Intern Med,2002,41(2):94-97.(in Chinese)陈隆典,张晓琦.胰性脑病与韦尼克脑病[J].中华内科杂志,2002,41(2):94-97.
    [15]HORNIK A,RODRIGUEZ PORCEL FJ,AGHA C,et al.Central and extrapontine myelinolysis affecting the brain and spinal cord.An unusual presentation of pancreatic encephalopathy[J].Front Neurol,2012,3:135.
    [16]OHKUBO T,SHIOJIRI T,MATSUNAGA T.Severe diffuse white matter lesions in a patient with pancreatic encephalopathy[J].J Neurol,2004,251(4):476-478.
    [17]DING X,LIU CA,GONG JP,et al.Pancreatic encephalopathy in24 patients with severe acute pancreatitis[J].Hepatobiliary Pancreat Dis Int,2004,3(4):608-611.
    [18]SUN GH,YANG YS,LIU QS,et al.Pancreatic encephalopathy and Wernicke encephalopathy in association with acute pancreatitis:a clinical study[J].World J Gastroenterol,2006,12(26):4224-4227.
    [19]LU XS,QIU F,LI YX,et al.Effect of lower-molecular weight heparin in the prevention of pancreatic encephalopathy in the patient with severe acute pancreatitis[J].Pancreas,2010,39(4):516-519.
    [20]QIU F,LU XS,HUANG YK.Protective effect of low-molecularweight heparin on pancreatic encephalopathy in severe acute pancreatic rats[J].Inflamm Res,2012,61(11):1203-1209.
  • 加载中
计量
  • 文章访问数:  2362
  • HTML全文浏览量:  16
  • PDF下载量:  456
  • 被引次数: 0
出版历程
  • 收稿日期:  2016-10-28
  • 出版日期:  2017-01-20
  • 分享
  • 用微信扫码二维码

    分享至好友和朋友圈

目录

    /

    返回文章
    返回