碘-125粒子植入近程放疗在肝胆胰恶性肿瘤中的应用

江旭; 杨继金; 李慧

doi:10.3969/j.issn.1001-5256.2016.12.014

碘-125粒子植入近程放疗在肝胆胰恶性肿瘤中的应用

DOI: 10.3969/j.issn.1001-5256.2016.12.014

第二军医大学附属长海医院介入治疗科

详细信息

中图分类号: R735;R730.55
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出版历程
- 出版日期: 2016-12-20

Clinical effect of brachytherapy with ~(125)I seed implantation in treatment of malignant hepatopancreatobiliary tumors

摘要

摘要: 碘-125(125I)粒子植入在预防肝癌术后早期复发,联合其他微创治疗方法根治性治疗早期肝癌取得了很好的疗效,同时也广泛应用于中晚期肝癌及门静脉癌栓的治疗。125I粒子用于治疗肝内胆管细胞癌、转移性肝癌等乏血供肿瘤,也取得了很好的局部控制率。125I粒子联合胆道支架可很好的解除恶性胆道梗阻的症状,再狭窄的时间明显延长。基于125I粒子植入的综合介入治疗,能显著改善胰腺癌患者的生活质量并延长生存期。125I粒子植入在临床上使用方便、安全,值得推广。
- 肝肿瘤 /
- 胆管肿瘤 /
- 胰腺肿瘤 /
- 碘放射性同位素 /
- 放射疗法
Abstract: Malignant hepatopancreatobiliary tumors are highly malignant and have poor prognosis.~(125)I seed implantation combined with other minimally invasive therapies for radical treatment of early liver cancer has achieved a good clinical effect in preventing early recurrence after liver cancer surgery. It is also used in the treatment of advanced liver cancer and portal vein tumor thrombosis.~(125)I seed has achieved a good local control rate in the treatment of tumors with a lack of blood supply,such as intrahepatic cholangiocellular carcinoma and metastatic liver cancer.~(125)I seed combined with biliary stenting can significantly relieve the symptoms of malignant biliary obstruction and extend the time to restenosis. Comprehensive interventional treatment based on~(125)I seed can significantly improve quality of life and extend survival time in patients with pancreatic cancer. Therefore,~(125)I seed implantation is safe and convenient in clinical practice and holds promise for clinical application.
- liver neoplasms /
- bile duct neoplasms /
- pancreatic neoplasms /
- iodine radioisotopes /
- radiotherapy

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参考文献(40)

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