IgG4相关自身免疫性肝炎诊治的研究进展

石晓东; 魏琪; 余敏; 刘星星; 贾志芳; 王越淇; 姜振宇

doi:10.3969/j.issn.1001-5256.2016.09.042

IgG4相关自身免疫性肝炎诊治的研究进展

DOI: 10.3969/j.issn.1001-5256.2016.09.042

1. 吉林大学第一医院风湿免疫科
2. 吉林大学第一医院干部病房
3. 马鞍山市人民医院风湿免疫科
4. 吉林大学第一医院临床流行病学中心

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中图分类号: R575.1
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出版历程
- 出版日期: 2016-09-20

Research advances in diagnosis and treatment of IgG4-associated autoimmune hepatitis

Department of Rheumatology, The First Hospital of Jilin University

摘要

摘要: 自身免疫性肝炎（AIH）是一种累及肝脏实质的慢性进展性炎症性疾病。近年来,对IgG4相关性疾病的研究日益增多,外国学者研究发现,AIH患者的肝脏亦有IgG4阳性浆细胞浸润,表明IgG4可能参与AIH的发病机制,进而认为这是AIH的特殊类型,称之为IgG4相关性AIH（IgG4-AIH）。对AIH与IgG4-AIH的诊治研究进展进行简要综述,从而加强临床医生对此类疾病的认知。
- 肝炎,自身免疫性 /
- 免疫球蛋白G /
- 诊断 /
- 治疗 /
- 综述
Abstract: Autoimmune hepatitis( AIH) is a chronic progressive inflammatory disease involving the liver parenchyma. In recent years,there have been more studies focusing on IgG4- associated diseases. Foreign scholars have found that patients with AIH also have IgG4- positive plasma cell infiltration in the liver,suggesting that IgG4 may be involved in the pathogenesis of AIH,and this disease is considered a special type of AIH and thus it is called IgG4- associated AIH( IgG4- AIH). This article reviews the research advances in the diagnosis and treatment of AIH and IgG4- AIH,so as to enhance clinical doctors' knowledge of such diseases.
- hepatitis,autoimmune /
- immunoglobulin G /
- diagnosis /
- therapy /
- review

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参考文献(21)

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