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慢性乙型肝炎免疫治疗新策略

刘诗 汤善宏 钟晓祝

引用本文:
Citation:

慢性乙型肝炎免疫治疗新策略

DOI: 10.3969/j.issn.1001-5256.2016.07.042
详细信息
  • 中图分类号: R512.62

New immunotherapeutic strategies for chronic hepatitis B

  • 摘要: 慢性乙型肝炎(CHB)是全球重要的传染病之一,目前主要的治疗药物为干扰素与核苷和核苷酸类药物,具有较好疗效,但尚未达到彻底清除人体内HBV的最终目标。因此,探索治疗新策略以及研发新的治疗药物有重要意义。HBV的持续感染与机体内免疫状态密切相关,目前研究表明免疫治疗有助于实现彻底治愈CHB。结合CHB患者的免疫状态,综述了Toll样受体激动剂、细胞治疗、治疗性疫苗等免疫治疗新策略的研究进展。

     

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  • 出版日期:  2016-07-20
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