原发性肝癌患者术后并发肺部感染的危险因素分析

艾叶青; 张诚华; 刘卉芳

doi:10.3969/j.issn.1001-5256.2016.07.024

原发性肝癌患者术后并发肺部感染的危险因素分析

DOI: 10.3969/j.issn.1001-5256.2016.07.024

中国人民解放军第一八○医院普通外科ICU

基金项目:

南京军区重点课题资助项目(12MA071)；

详细信息

中图分类号: R735.7;R563.1
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出版历程
- 出版日期: 2016-07-20

Risk factors for postoperative pulmonary infection in patients with primary liver cancer

Research funding:

摘要

摘要: 目的回顾性分析原发性肝癌患者术后导致肺部感染的危险因素,为今后临床治疗上采取相应预防措施提供参考依据。方法选取2011年5月-2015年12月于中国人民解放军第一八○医院肝病科就诊的原发性肝癌患者286例,根据术后是否发生肺部感染分为感染组（n=36）和非感染组（n=250）。对可能引起术后肺部感染的诸多因素进行分析,计量资料组间比较采用t检验,计数资料组间比较采用χ2检验,Logistic多因素回归分析术后并发肺部感染的危险因素。结果单因素分析显示,两组患者年龄分布、吸烟史、糖尿病、术中输血量、腹腔引流管留置时间比较,差异均有统计学意义（P值均<0.05）;进一步多因素Logistic回归分析显示,吸烟史、糖尿病、术中输血量和腹腔引流管留置时间为患者术后并发肺部感染的独立危险因素（P值均<0.05）。麻醉相关因素中使用一次性器械和围手术期抗菌药的使用均使患者术后肺部感染率下降（P值均<0.05）。结论吸烟史、糖尿病、术中输血量、腹腔引流管留置时间、麻醉使用一次性器械和围手术期抗菌药的使用情况均为原发性肝癌患者术后并发肺部感染的危险因素,针对危险...
- 肝肿瘤 /
- 感染 /
- 危险因素
Abstract: Objective To investigate the risk factors for postoperative pulmonary infection in patients with primary liver cancer through a retrospective analysis,and to provide a reference for appropriate preventive measures in clinical treatment. Methods A total of 286 patients with liver cancer who visited Department of Hepatology,180 Hospital of PLA,from May 2011 to December 2015 were enrolled,and according to the presence or absence of postoperative pulmonary infection,these patients were divided into infection group( 36 patients) and non-infection group( 250 patients). The factors for postoperative pulmonary infection were analyzed. The t- test was used for comparison of continuous data between groups,the chi- square test was used for comparison of categorical data between groups,and logistic multivariate regression analysis was used to analyze the risk factors for postoperative pulmonary infection. Results The univariate analysis showed that age distribution,smoking history,diabetes,intraoperative blood transfusion volume,and the indwelling time of abdominal drainage tube showed significant differences between the two groups( all P < 0. 05). The multivariate analysis showed that smoking history,diabetes,intraoperative blood transfusion volume,and the indwelling time of abdominal drainage tube were independent risk factors for postoperative pulmonary infection in patients with primary liver cancer( all P < 0. 05). Among the anesthesia- related factors,application of single- use medical devices and perioperative antibacterial agents significantly reduced the incidence rate of postoperative pulmonary infection( both P < 0. 05).Conclusion Smoking history,diabetes,intraoperative blood transfusion volume,the indwelling time of abdominal drainage tube,no use of single- use medical devices during anesthesia,and no use of perioperative antibacterial agents are risk factors for postoperative pulmonary infection in patients with primary liver cancer. Corresponding preventative and treatment methods can effectively prevent the development of postoperative pulmonary infection.
- liver neoplasms /
- infection /
- risk factors

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参考文献(15)

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