调节性T淋巴细胞与HBV感染慢性化的关系

何俊楠; 赵守松

doi:10.3969/j.issn.1001-5256.2016.02.036

调节性T淋巴细胞与HBV感染慢性化的关系

DOI: 10.3969/j.issn.1001-5256.2016.02.036

蚌埠医学院第一附属医院感染病科

详细信息

中图分类号: R512.62
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出版历程
- 收稿日期: 2015-07-29
- 出版日期: 2016-02-20

Research advances in association between regulatory T cells and hepatitis B virus infection

Department of Infectious Diseases,The First Affiliated Hospital of Bengbu Medical College

摘要

摘要: 调节性T淋巴细胞是抑制机体免疫应答,诱导机体免疫耐受的一种T淋巴细胞亚群,是近年来免疫学领域研究的热点之一。调节性T淋巴细胞功能紊乱和数量上的变化与自身免疫性疾病、感染性疾病、肿瘤免疫耐受、移植排斥以及过敏性疾病的进程和治疗密切相关。归纳了近几年调节性T淋巴细胞的表面标志、免疫机制及其与乙型肝炎发病和抗病毒治疗过程的关系。
- 肝炎,乙型,慢性 /
- T淋巴细胞,调节性 /
- T淋巴细胞,辅助诱导 /
- 综述
Abstract: Regulatory T cells are a subset of T cells,and can inhibit the body's immune response and induce immune tolerance,which has become one of the hot topics in the field of immunological research in recent years. Regulatory T cell dysfunction and the change in the number of regulatory T cells are closely associated with the progression and treatment of autoimmune diseases,infectious diseases,tumor immune tolerance,transplant rejection,and allergic diseases. This article summarizes the surface markers and immunological mechanism of regulatory T cells,as well as the association of regulatory T cells with the pathogenesis of hepatitis B and antiviral therapy.
- hepatitis B,chronic /
- T-lymphocytes,regulatory /
- T-lymphocytes,helper-inducer /
- review

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参考文献(32)

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