局部消融在肝细胞癌治疗中的应用

朱晓黎; 沈健

doi:10.3969/j.issn.1001-5256.2016.01.008

局部消融在肝细胞癌治疗中的应用

DOI: 10.3969/j.issn.1001-5256.2016.01.008

朱晓黎,
沈健

苏州大学附属第一医院介入科

基金项目:

2012年第九批“六大人才高峰”项目(WS-052)； 2013年度江苏省第四期“333工程”科研资助项目(BRA2013287)；

详细信息

中图分类号: R735.7
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出版历程
- 收稿日期: 2015-11-03
- 出版日期: 2016-01-20

Application of local ablative therapies for hepatocellular carcinoma

Department of Interventional Radiology,The First Affiliated Hospital of Soochow University

Research funding:

摘要

摘要: 手术切除和肝移植被认为是肝细胞癌(HCC)根治性治疗手段,但仅有10%~20%的HCC患者能接受这些治疗。近些年来,射频消融、微波消融、冷冻消融及新近出现的不可逆电穿孔消融等局部治疗方法逐渐成为无法手术患者的替代治疗。除了局部控制肿瘤生长改善预后外,消融技术还有助于肿瘤降级以便二次切除。重点介绍了射频消融及联合其他治疗手段治疗HCC的进展,对射频消融与其他局部消融进行了比较,简述了智能导航技术在辅助消融中的应用,认为随着影像医学的发展以及其他相关领域的进步,未来消融技术在临床应用中将更加广泛。
- 癌,肝细胞 /
- 局部消融术 /
- 治疗
Abstract: Hepatocellular carcinoma( HCC) is a common malignant tumor in the world,and surgical resection and liver transplantation are two radical treatment modalities,but only 10%- 20% of all patients can receive such treatments. In recent years,local therapies including radiofrequency ablation,microwave ablation,cryoablation,and the irreversible electroporation ablation which appeared recently have gradually become the alternative therapies for the patients who are unable to undergo surgery. In addition to local tumor growth control and improvement in survival outcomes,the ablation technology also helps to downgrade tumor for secondary resection. This article focuses on the research progress in radiofrequency ablation alone and in combination with other therapies in the treatment of HCC,compares radiofrequency ablation with other local ablative therapies,and briefly introduces the application of intelligent navigation technology in adjuvant ablation.With the development of medical imaging and progress in related fields,the ablation technology will be widely applied in clinical practice in the future.
- carcinoma,hepatocellular /
- local ablation /
- therapy

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