PDF下载 ( 1527 KB)
Discussion on idiosyncratic drug-induced liver injury in children
-
摘要:
近年来,特异质性药物性肝损伤(IDILI)发病率逐年升高,危害严重。介绍了IDILI的发病率、发病机制、临床诊断和处理原则。因儿童IDILI的相关大数据文献较少,故简述了有关IDILI患儿的诊治经验,认为减少和预防儿童IDILI的发生,需从严格掌握用药指征入手,同时应进一步开展分子水平检测以及大力推进精确化医疗方式。
Abstract:In recent years,the incidence of idiosyncratic drug- induced liver injury( IDILI) has been increasing,posing a threat to human health. This article reviews the incidence,pathogenesis,and the principles of clinical diagnosis and treatment of IDILI. Because there is limited literature on IDILI in children,so this article simply describes the experience in the diagnosis and treatment of IDILI in children. It is considered that to reduce the incidence of IDILI in children,drug indications should be strictly followed,and molecular test and accurate medical treatment should be promoted.
-
Key words:
- drug-induced liver injury /
- diagnosis /
- therapy /
- child
-
本文二维码
计量
- 文章访问数: 2191
- HTML全文浏览量: 18
- PDF下载量: 512
- 被引次数: 0
下载:
