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Mechanisms and treatment of cholestasis- induced liver fibrosis
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摘要: 任何导致胆汁流异常的病理状态均称为胆汁淤积,肝纤维化是肝脏对于损伤的修复反应,两者均是肝脏疾病过程中的一种病理状态。在胆汁淤积和肝纤维化概述的基础上,论述了胆汁淤积导致肝纤维化的机制及药物治疗,认为防治胆汁性肝纤维化仍需进一步研究。Abstract: Any pathological state that causes disturbance in bile flow is called cholestasis. Liver fibrosis is a repair response to liver injury.Both cholestasis and liver fibrosis are pathological states in liver diseases. This paper briefly introduces cholestasis and liver fibrosis,and illustrates the mechanisms and therapeutic drugs for cholestasis- induced liver fibrosis. Further study is needed to prevent and treat cholestasis- induced liver fibrosis.
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Key words:
- liver cirrhosis /
- cholestasis /
- therapy
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