肝硬化患者门静脉、肝动脉血流参数与肝硬度值的关系

程小飞; 梁雄波; 熊晓青; 唐永丽; 陈萍

doi:10.3969/j.issn.1001-5256.2014.11.022

肝硬化患者门静脉、肝动脉血流参数与肝硬度值的关系

DOI: 10.3969/j.issn.1001-5256.2014.11.022

中山市第二人民医院影像科

基金项目:

广东省中山市科技局社会发展公关计划项目(20132A050)；

详细信息

中图分类号: R575.2
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出版历程
- 收稿日期: 2014-03-05
- 出版日期: 2014-11-20

Relationship between hemodynamic changes of portal vein and hepatic artery measured by color Doppler ultrasound and FibroScan value in patients with liver cirrhosis

Department of Ultrasound, The Second People's Hospital of Zhongshan

Research funding:

摘要

摘要: 目的探讨应用彩色多普勒超声显像仪以及瞬时弹性成像（FibroScan）观察和分析肝硬化患者的门静脉、肝动脉血流动力学改变的意义。方法选择2010年3月至2013年12月本院收治的乙型肝炎肝硬化患者192例,另选健康人100例,使用彩色超声多普勒显像仪检测门静脉平均血流速度（PVVmean）、肝动脉搏动指数（HAPI）、肝动脉阻力指数（HARI）;同时进行FibroScan检测,检测结果以肝硬度（LSM）表示。计量资料以均数±标准差（x±s）表示,组间比较采用t检验。结果肝硬化患者HAPI、HARI和LSM分别为1.56±0.24、0.73±0.05和25.38±7.73 kPa,明显高于正常对照组的1.36±0.14、0.65±0.07和7.8±3.6kPa,t值分别为8.980、10.158、26.478,P值均<0.05);而肝硬化患者PVVmean为（14.43±1.86）cm/s,明显低于正常对照组（17.35±0.56）cm/s（t=20.076,P<0.05）。LSM与肝硬化患者HAPI和HARI呈正相关,相关系数r分别为0.59、0.66,P值均<0.0...
- 肝硬化 /
- 门静脉 /
- 肝动脉 /
- 血流动力学 /
- 超声检查,多普勒,彩色 /
- 弹性成像技术
Abstract: Objective To explore the relationship between hemodynamic changes of the portal vein and hepatic artery measured by color Doppler ultrasound and FibroScan value in patients with liver cirrhosis. Methods A total of 192 patients with hepatitis B cirrhosis who were admitted to our hospital from March 2010 to December 2013, as well as 100 healthy persons, were recruited. The mean portal vein blood flow velocity (PVVmean) , hepatic artery pulsatility index ( HAPI) , and hepatic artery resistance index ( HARI) were measured by color Doppler ultrasound. FibroScan was also carried out. All data were statistically analyzed using SPSS 13. 0. Continuous data were expressed as mean ± SD and compared between groups by t- test. Results The HAPI, HARI, and FibroScan value of the patient group were 1. 56 ±0. 24, 0. 73 ± 0. 05, and 25. 38 ± 7. 73, respectively, significantly higher than those of the control group (1. 36 ± 0. 14, 0. 65 ± 0. 07, and7. 8 ± 3. 6) (P < 0. 05) ; the PVVmean of the patient group was 14. 43 ± 1. 86, significantly lower than that of the control group (17. 35 ±0. 56) (P < 0. 05) . FibroScan value was positively correlated with HAPI and HARI (r1= 0. 59, r2= 0. 66, P < 0. 001) , but negatively correlated with PVVmean (r =- 0. 64, P < 0. 001) . Conclusion The liver stiffness assessed by FibroScan and the hemodynamic changes of the portal vein and hepatic artery measured by color Doppler ultrasound are vitally important for evaluating the severity of liver cirrhosis.
- liver cirrhosis /
- portal vein /
- hepatic artery /
- hemodynamics /
- ultrasound, doppler, color /
- elasticity imaging techniques

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参考文献(8)

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