中文English
ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R

留言板

尊敬的读者、作者、审稿人, 关于本刊的投稿、审稿、编辑和出版的任何问题, 您可以本页添加留言。我们将尽快给您答复。谢谢您的支持!

姓名
邮箱
手机号码
标题
留言内容
验证码

螺杆菌感染与慢性肝病研究现状与进展

池肇春

引用本文:
Citation:

螺杆菌感染与慢性肝病研究现状与进展

DOI: 10.3969/j.issn.1001-5256.2014.09.027
详细信息
  • 中图分类号: +

Current status and progress in research on helicobacter infection and chronic liver diseases

  • 摘要: 有关螺杆菌感染与肝病相关的研究逐渐增加,主要是研究螺杆菌对肝病的影响,而肝病对螺杆菌的作用研究甚少。介绍了肝病时螺杆菌的细菌学、流行率,螺杆菌引起肝病的发病机制和诊断。至目前为止现已得到共识与人类肝病相关的螺杆菌有3种,即H.pylori、H.heilmanni和H.cinaedi,其中主要是H.pylori的研究,对于后两者研究不多,而肝螺杆菌属于H.pylori的1个新型。研究显示今后应主要在发病机制和预防上做更深入的研究。

     

  • [1]CHI ZC, QI YQ, DONG QJ, et al.Diagnosis and treatment of Helicobacter pylori infection and related diseases[M].Beijing:Military Medical Science Press, 2009:232-241. (in Chinese) 池肇春, 亓玉琴, 董全江, 等.幽门螺杆菌感染及其相关疾病的诊断与治疗[M].北京:军事医学科学出版社, 2009:232-241.
    [2] SARK SA, BADRAH GA, SHEIR RA.Histological and histochemical alterations in liver of chronic hepatitis C patients with H.pylori infection[J].Biomed Pharmacother, 2013, 67 (5) :367-374.
    [3] LE ROUX-GOGLIN E, VARON C, SPUUL P, et al.Helicobacter infection induces podosome assembly in primary hepatocytes in vitro[J].Eur J Cell Biol, 2012, 91 (3) :161-170.
    [4] ZULLO A, SANCHEZ-METE L, HASSAN C, et al.Helicobacter pylori density and CagA status in cirrhosis patients:a case-control study[J].J Gastroenterol Hepatol, 2004, 19 (10) :1174-1178
    [5]VILLALAN R, MAROJU NK, KATE V, et al.Helicobacter pylori eradication indicated in cirrhotic patients with peptic ulcer disease?[J].Gastroenterol, 2006, 27 (4) :166-168.
    [6]NAM YJ, KIM SJ, SHIN WC, et al.Gastric pH and H.pylori diagnosis in patients with liver cirrhosis[J].Korean J Hepatol, 2004, 10 (3) :216-222.
    [7] LO GH, YU HC, CHAN YC, et al.The effects of eradication of Helicobacter pylori on the recurrence of duodenal ulcers in patients with cirrhosis[J].Gastrointest Endosc, 2005, 62 (3) :350-356.
    [8]WYSZOMIRSKA RM, RIBEIRO LT, MONTEIRO JS, et al.Association between Helicobacter pylori infection and gastroduodenal lesions in patients with chronic liver disease[J].Arg Gastroenterol, 2009, 46 (4) :256-260.
    [9] QUEIROZ DM, ROCHA AM, ROCHA GA, et al.Association between Helicobacter pylori infection and cirrhosis in patients with chronic hepatitis C virus[J].Dig Dis Sci, 2006, 51 (2) :370-373.
    [10]URSO G, INTERLANDI D, PUGLISI M, et al.Role of Helicobacter pylori in patients with portal hypertensi gastropathy by liver cirrhosis hepatitis C virus-related[J].Minerva Gastroenterol Dietol, 2006, 52 (3) :303-308.
    [11] STALKE P, AL-SOUD WA, BIELKAWSKI KP, et al.Detection of Helicobacter species in liver and stomach tissues patients with chronic liver disease using polymerase chain reaction-denaturing gradient gel electrophoresis and immunohistochemistry[J].Scand J Gastroenterol, 2005, 40 (9) :1032-1041.
    [12] WANG MY, YUE JY, ZHANG YX, et al.Helicobacter pylori infection in asymptomatic HBV carriers, alcohol users and normal adult population in Shandong province, China[J].Clin Res Hepatol Gastroenterol, 2011, 35 (8-9) :560-562.
    [13]CHEN R, CHEN XP, LIN QX, et al.Detection of Helicobacter species related genes coding for 16S rRNA in the liver tissue of patients with chronic liver disease[J].J South Med Univ, 2010, 30 (1) :131-132. (in Chinese) 陈仁, 陈小苹, 林秋雄, 等.慢性肝脏疾病患者肝组织中螺杆菌相关基因16SrRNA的检测[J].南方医科大学学报, 2010, 30 (1) :131-132.
    [14]DIZERZANOWSKA-FANGRAT K, NILSSON I, WOZNIAK M, et al.Lack of an association between Helicobacter infection and autoimmune hepatitis in children[J].Pol J Microbiol, 2006, 55 (2) :157-159.
    [15]BOUTIN SR, SHEN Z, ROGERS AB, et al.Different Helicobacter hepaticus strains with variable genoma content induce various degrees of hepatitis[J].Infect Immun, 2005, 73 (12) :8449-8452.
    [16] LE ROUX-GOGLIN E, DUBUS P, ASENCIO C, et al.Hepatic lesions observed in hepatitis C virus transgenic mice infected by Helicobacter hepaticus[J].Helicobacter, 2013, 18 (1) :33-40.
    [17] GARCIA A, ZENG Y, MUTHUPALANI S, et al.Helicobacter hepaticus-induced liver tumor promotion is associated with increased serum bile acid and a persistent microbial-induced immune responses[J].Cancer Res, 2011, 71 (7) :2529-2540.引证本文:CHI ZC.Current status and progress in research on helicobacter infection and chronic liver diseases[J].J Clin Hepatol, 2014, 30 (8) :944-947. (in Chinese) 池肇春.螺杆菌感染与慢性肝病研究现状与进展[J].临床肝胆病杂志, 2014, 30 (8) :944-947.
  • 加载中
计量
  • 文章访问数:  2586
  • HTML全文浏览量:  11
  • PDF下载量:  598
  • 被引次数: 0
出版历程
  • 收稿日期:  2013-11-27
  • 出版日期:  2014-09-20
  • 分享
  • 用微信扫码二维码

    分享至好友和朋友圈

目录

    /

    返回文章
    返回