髓样抑制细胞在促进肿瘤发生中的作用

纪柏; 刘亚辉

doi:10.3969/j.issn.1001-5256.2014.09.026

髓样抑制细胞在促进肿瘤发生中的作用

DOI: 10.3969/j.issn.1001-5256.2014.09.026

纪柏,
刘亚辉

吉林大学第一医院肝胆胰外科二组

基金项目:

吉林省科技厅青年基金资助项目(20140520026JH)；

详细信息

中图分类号: R735.7
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出版历程
- 收稿日期: 2014-07-08
- 出版日期: 2014-09-20

Research advances in role of myeloid- derived suppressor cells in tumorigenesis

Ji Bo,
Liu YaHui

Department of Hepatobiliary and Pancreatic Surgery, The First Hospital of Jilin University

Research funding:

摘要

摘要: 总结了髓样抑制细胞(MDSC)在促进炎症发生和肿瘤细胞的免疫逃逸中发挥的作用,以及促进肿瘤发生发展的作用机制。可为以后探讨肝纤维化和肝癌发病的免疫学机制提供一条新的思路,也将有利于未来寻找肝纤维化和肝癌治疗的有效靶点。
- 肝肿瘤 /
- 肝硬化 /
- 髓样抑制细胞 /
- 综述
Abstract: The role of myeloid- derived suppressor cells ( MDSCs) in promoting inflammatory response and immune escape of tumor cells and the mechanism by which MDSCs promote the development and progression of tumors are reviewed. This could provide a new way for the investigation of immunological mechanism of liver fibrosis and liver cancer. Besides, MDSCs may be an effective therapeutic target for liver cirrhosis and liver cancer.
- liver neoplasms /
- liver cirrhosis /
- myeloid derived suppressor cells /
- review

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