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T细胞免疫球蛋白黏蛋白分子3与HBV感染的研究进展

董杰 申焕君 杨晓菲 赵荣荣 张野 赵燕燕 黄长形 连建奇

引用本文:
Citation:

T细胞免疫球蛋白黏蛋白分子3与HBV感染的研究进展

DOI: 10.3969/j.issn.1001-5256.2014.09.025
基金项目: 

国家自然科学基金资助项目(31370856); 

详细信息
  • 中图分类号: R512.62

Research progress in TIM-3 and HBV infection

Research funding: 

 

  • 摘要: 研究发现T细胞免疫球蛋白黏蛋白分子(TIM)3与许多疾病的发病相关联。HBV感染机体时,TIM-3作为一个负性免疫调节分子,在CD8+T细胞上的表达明显增高,这表明它与HBV的发病机制密切相关。从TIM-3的生物学特性、HBV疾病转归和治疗靶点等方面回顾总结了TIM-3与HBV感染的最新研究进展,认为TIM-3将会成为HBV治疗的新靶点。

     

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  • 收稿日期:  2013-11-19
  • 出版日期:  2014-09-20
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