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One case of vanishing bile duct syndrome
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摘要: <正>胆管消失综合征(VBDS)最早见Sherlock报道,是以肝内胆管减少为病理学特征,以胆汁淤积为主要临床表现的综合征[1]。病因中包括发育、代谢和免疫学异常、血管病变、感染、淋巴病、药物等因素,真正病因及发病机制尚不明确,临床较为少见[2]。1病历资料患者,女,56岁,无业,因"间断乏力1年"于2011年4月8日入院。既往19年前行剖宫产手术;口服避孕药17年(为短
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Key words:
- bile ducts, intrahepatic /
- cholestasis /
- case reports
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[1]OPPENHEIMER AP, KOH C, McLAUGHLIN M, et al.Vanishing bile duct syndrome in human immunodeficiency virus infected adults:a report of two cases[J].World J Gastroenterol, 2013, 19 (1) :115-121. [2]BHAYANA H, APPASANI S, THAPA BR, et al.Lamotrigineinduced vanishing bile duct syndrome in a child[J].J Pediatr Gastroenterol Nutr, 2012, 55 (6) :e147-e148. [3]KAHN E.Biliary atresia revisite[J].Pediatr Dev Pathol, 2004, 7 (2) :109-124. [4]HUMAR A, WASHBURN K, FREEMAN R, et al.An assessment of interactions between hepatitis C virus and herpesvirus reactivation in liver transplant recipientsusing molecular surveillance[J].Liver Transpl, 2007, 13 (10) :1422-1427. [5]ARTHURS SK, EID AJ, PEDERSEN RA, et al.Delayed-onset primary cytomegalovirus disease after liver transplantation[J].Liver Transpl, 2007, 13 (12) :1703-1709. [6]DESMET VJ.Vanishing bile duct syndrome in drug-induced liver disease[J].J Hepatol, 1997, 26 (Suppl 1) :31-35. [7]PAUMGARTNER G, BEUERS U.Ursodeoxycholic acid in cholest atic liver disease:mechanisms of act ion and therapeutic use revisited[J].Hepatology, 2002, 36 (3) :525-531. [8]NAKANUMA Y, TSUNEYAMA K, HARADA K.Pathology and pathogenesis of intrahepatic bile duct loss[J].J Hepatobiliary Pancreat Surg, 2001, 8 (4) :303-315. [9]GEUBEL AP, SEMPOUX CL.Drug and toxin-induced bile duct disorders[J].J Gastroenterol Hepatol, 2000, 15 (11) :1232-1238. -
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