肝肿瘤热消融的规范化治疗

陈敏华

doi:10.3969/j.issn.1001-5256.2013.08.001

肝肿瘤热消融的规范化治疗

DOI: 10.3969/j.issn.1001-5256.2013.08.001

陈敏华

北京大学肿瘤医院
北京市肿瘤防治研究所超声科

基金项目:

首都市民健康项目培育(Z111107067311026)；国家自然科学基金青年科学基金(81101745)；

详细信息

中图分类号: R735.7
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出版历程
- 出版日期: 2013-08-20

Standardization of thermal ablation in treatment of liver tumor

Chen MinHua

Research funding:

摘要

摘要:
热消融已成为同手术切除、肝移植治疗肝癌的三大根治方法,其疗效及微创性越来越受到重视。然而中国肝癌须行消融治疗的患者多数肝功能差,治疗难度大,复发率高而影响疗效及普及推广。重点简述影像指导下肝肿瘤热消融规范化治疗的原则和方案策略,旨在提高疗效及本项技术的安全性。
- 肝肿瘤 /
- 热消融 /
- 肿瘤治疗方案
Abstract:
Thermal ablation ranks along with surgical resection and liver transplantation as a major radical treatment for liver tumor, and more and more attention has been paid to its efficacy and minimal invasiveness.However, the majority of Chinese patients who need ablation treatment have poor liver function, so the treatment is challenging, with a high recurrence rate.That has a negative impact on the efficacy and application of this technique.The principle and strategy of standardized image-guided thermal ablation in the treatment of liver tumor were briefly reviewed, with the aim of improving the efficacy and safety of this technique.
- liver neoplasms /
- thermal ablation /
- antineplastic protocols

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参考文献(13)

[1] Chinese Expert Consensus Statement, Chinese Society of Liver Cancer (CSLC) , Chinese Society of Cinical Oncology (CSCO) , Liver Cancer Group, Chinese Society of Hepatol.Guidelines for radiofrequency abla-tion therapy of liver cancer[J].J Clin Hepatol, 2011.27 (3) :236-242.中国抗癌协会肝癌专业委员会, 中国抗癌协会临床肿瘤学协作委员会, 中华医学会肝病学分会肝癌学组.肝癌射频消融治疗规范的专家共识[J].临床肝胆病杂志, 2011, 27 (3) :236-242. (in Chi-nese)

[2]SALA M, LLOVET JM, VILANA R, et al.Initial response to percuta-neous ablation predicts survival in patients with hepatocellular carcino-ma[J].Hepatology, 2004, 40 (6) :1352-1360.

[3]CHEN MH, YANG W, YAN K, et al.Large liver tumors:protocol for radiofrequency ablation and its clinical application in110pa-tients[J].Radiology, 2004, 232 (1) :260-271.

[4]ZHANG YJ, LIANG HH, CHEN MS, et al.Hepatocellular carci-noma treated with radiofrequency ablation with or without ethanol in-jection:a prospective randomized trial[J].Radiology, 2007, 244 (2) :599-607.

[5]CHEN MH, GOLDBERG SN.Radiofrequency ablation of liver tumor-basic and clinical studies[M].Beijing:People's Medical Publishing House, 2009:274-346. (in Chinese) 陈敏华, Goldberg SN.肝癌射频消融-基础与临床[M].北京:人民卫生出版社, 2009:274-346.

[6]MORIMOTO M, NUMATA K, KONDOU M, et al.Midterm out-comes in patients with intermediate-sized hepatocellualr carcino-ma:a randomized controlled trial for determining the efficacy of ra-diofrequency ablation combined with transcatheter arterial chemoem-bolization[J].Cancer, 2010, 116 (23) :5452-5460.

[7]HOU YB, CHEN MH, YAN K, et al.Adjuvant percutaneous ra-diofrequency ablation of feeding artery of hepatocellular carcinoma before treatment[J].World J Gastroenterol, 2009, 15 (21) :2638-2643.

[8]WU W, CHEN MH, FU Y, et al.Long-term efficacy of radiofre-quency ablation in446patients with hepatocellular carcinoma[J].J Peking Univ:Health Sci, 2010, 42 (6) :716-721. (in Chinese) 吴薇, 陈敏华, 付颖, 等.446例肝细胞癌射频消融治疗远期疗效[J].北京大学学报:医学版, 2010, 42 (6) :716-721.

[9]YANG W, CHEN MH, WANG MQ, et al.Combination therapy ofradiofrequency ablation and transarterial chemoembolization in re-current hepatocellular carcinoma after hepatectomy compared with single treatment[J].Hepatol Res, 2009, 39 (3) :231-240.

[10]YAO FY, KINKHABWALA M, LABERGE JM, et al.The impact of preoperative loco-regional therapy on outcome after liver trans-plantation for hepatocellular carcinoma[J].Am J Transplant, 2005, 5 (4Pt1) :795-804.

[11] TANG Y, PAN C, WU HT, et al.To prevent the replase of hepato-cellular carcinoma after liver transplantation by radiofrequency abla-tion pre and during the operation[J].Chin J Organ Transplant, 2010, 31 (12) :765-766. (in Chinese) 唐缨, 潘澄, 武红涛, 等.术前和术中应用射频消融技术处理病肝预防肝移植术后肝癌复发[J].中华器官移植杂志, 2010, 31 (12) :765-766.

[12]SHI XJ, JIN X, DONG JH, et al.Outcomes of loco-regional ther-apy for down-staging of hepatocellular carcinoma prior to liver transplantation[J].Hepatobiliary Pancreat Dis Int, 2011, 10 (2) :143-150.

[13]WU J, YANG W, YIN S, et al.Role of contrast-enhanced ultra-sonography in percutaneous radiofrequency ablation of liver metasta-ses and efficacy evaluation[J].Chin J Cancer Res, 2013, 25 (2) :143-154.

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