免疫细胞在慢性乙型肝炎免疫耐受机制中的作用

李俊卿; 周俊英

免疫细胞在慢性乙型肝炎免疫耐受机制中的作用

河北医科大学第三医院感染科

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中图分类号: R512.62
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出版历程
- 出版日期: 2011-04-20

The role of immune cells in immune tolerance mechanisms towards chronic hepatitis B

摘要

摘要: 机体对乙型肝炎病毒(HBV)的免疫耐受是HBV感染慢性化的主要机制。急性、自限性HBV感染过程中存在强烈的、多特异性的细胞免疫应答。而在慢性感染者这种反应明显减弱,存在免疫耐受。本文旨在阐述免疫细胞在HBV免疫耐受机制中可能发挥的作用。
- 肝炎病毒,乙型 /
- 免疫耐受 /
- 树突细胞 /
- T淋巴细胞,辅助诱导 /
- T淋巴细胞 /
- 肝炎,乙型,慢性
Abstract: Immune tolerance to hepatitis B virus (HBV) is the major chronicity mechanism of HBV infection.Cell-mediated immune responses to HBV antigens are vigorous and multispecific in acute, self-limited infections, whereas in chronic infection the response was significantly attenuated with immune tolerance.In this article, the role of immune cells in the mechanisms of immune tolerance was reviewed.
- hepatitis B virus /
- immune tolerance /
- dendritic cells /
- T-lymphocytes /
- helper-inducer /
- T-lymphocytes

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参考文献(22)

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