PDF下载 ( 167 KB)
A retrospective analysis of 145 cases with decompensation cirrhosis hyponatremia
-
摘要: 目的探讨肝硬化失代偿期患者不同血清钠水平与病情严重度的关系。方法回顾性分析我科收治145例肝硬化腹水伴低钠血症患者,根据其入院时血清钠水平分为低钠血症轻、中、重度组,比较3组肝肾功能、凝血功能、Child-Pugh评分、主要并发症、低钠纠正效果及病死率。结果患者低钠血症程度与肝肾功能、凝血功能、Child-Pugh分级、主要并发症、低钠纠正效果及病死率均具有相关性（P<0.05,P<0.01）,仅血清球蛋白在3组间差异无显著性（P>0.05）。结论肝硬化失代偿期患者的血清钠水平与其病重程度相关,监测血清钠水平可作为判断肝硬化腹水病情严重程度的重要指标之一。Abstract: Objective To investigate the relationship between serum sodium level and severity of the disease in decompensated liver cirrhosis patients.Methods 145 cirrhosis and ascites patients with hyponatremia were studied retrospectively.The patients were divided into light, moderate and severe hyponatremia groups according to their serum sodium levels.Clinical data including hepatonephric function, blood coagulation, Chind-Pugh score, main complications, effect of correcting hyponatremia and mortality were compared among the groups.Results The degree of hyponatremia were related to their hepatonephric function, blood coagulation, Child-Pugh classification, main complications, effect of correcting hyponatremia and mortality (P<0.05, P<0.01) .The serum globulin level among the three groups had no significant difference (P>0.05) .Conclusion The serum sodium level in decompensated cirrhotic patients is correlated with the disease severity and can be used as an important indicator.
-
Key words:
- cirrhosis ascites /
- hyponatremia /
- retrospective analysis
-
[1]许慧阳, 侯为顺, 蒯荟芬.血钠水平在肝硬化中的临床意义[J].实用全科医学, 2006, 4 (3) :278-279. [2]中华医学会.病毒性肝炎防治方案[J].中华肝脏杂志, 2000, 8 (6) :324-329. [3] 陈灏珠.实用内科学[M].第10版.北京:人民卫生出版社, 1997:1673. [4]Gines P, Jimnez W.Aquaretic agent s:a new potential treatment of dilutional hyponat remia in cirrhosis[J].J Hepatol, 1999, 24 (4) :506-512. [5]李卫东, 宫彦英, 曲韬.肝硬化腹水低钠血症52例转归分析[J].现代医学, 2004, 32 (2) :95-96. [6]Bradley EA, Reidy JF, Forman RG, et al.Transcatheter uterine ar-tery embolisation to treat large uterine fibroids[J].Br J Obstet Gyne-col, 1998, 105 (2) :235. [7]李井华, 罗忠金.肝硬化失代偿期并发低钠血症的原因及治疗现状[J].实用临床医学, 2008, 9 (9) :136-137. [8]曾欣, 林勇, 谢渭芬.关于肝硬化腹水治疗中“限钠”之我见[J].中华消化杂, 2007, 27 (5) :331-333. [9]Forman LM, Lucey MR.Predicting the prognosis of chronic liver dis-ease:an evolution fromChild to MELD.Mayo End-stage Liver Dis-ease[J].Hepatology, 2001, 33 (2) :473-475. [10]方国平, 张锁才, 孔启源, 等.60例肝炎后肝硬化腹水的低钠血症治疗及转归分析[J].肝脏, 2002, 7 (1) :32-33. -
本文二维码
计量
- 文章访问数: 2927
- HTML全文浏览量: 25
- PDF下载量: 901
- 被引次数: 0
下载:
