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Clinical and laboratory characteristics of male patients with primary biliary cirrhosis
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摘要:
<正>原发性胆汁性肝硬化(primary biliary cirrhosis,PBC)是一种可能与自身免疫有关的慢性进行性胆汁淤积性肝脏疾病,主要发生于中老年女性(男∶女比例为1∶9),病理表现为肝内胆管非化脓性炎症破坏,从而导致胆汁淤积,发生肝纤维化及肝硬化。男
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[1]Lohse AW, zum Buschenfelde KH, Franz B, et al.Characterization of the overlap syndrome of primary biliary cirrhosis (PBC) and auto-immune hepatitis:evidence for it being a hepatitic form of PBC in ge-netically susceptible individuals[J].J Hepatology, 1999, 29 (4) ∶1078-1084. [2]Joshi S, Cauch-Dudek K, Wanless IR, et al.Primary biliary cir-rhosis with additional features of autoimmune hepatitis:response to therapy with ursodeoxycholic acid[J].J Hepatology, 2002, 35 (2) ∶409-413. [3]HeurguéA, Vitry F, Diebold MD, et al.Overlap syndrome of pri-mary biliary cirrhosis and autoimmune hepatitis:a retrospective study of115cases of autoimmune liver disease[J].J Gastroenterol Clin Bi-ol, 2007, 31 (1) ∶17-25. [4]LF L, Adami HO, Sparèn P, et al.1994.Cancer risk in primary biliary cirrhosis:A population based study from Sweden[J].J Hepa-tology, 2005, 20 (1) ∶101-104. [5]Nijhawan P K, Therneau T M, Dickson E R, et al.1999.Incidence of cancer in primary biliary cirrhosis:the Mayo experience[J].J Hepatology, 2003, 29 (5) ∶1396-1398. [6]Jones D E, Metcalf J V, Collier J D, et al.1997.Hepatocellular carcinoma in primary biliary cirrhosis and its impact on outcomes[J].J Hepatology, 2003, 26 (5) ∶1138-1142. [7]Shibuya A, Tanaka K, Miyakawa H, et al.Hepatocellular carcinoma and survival in patients with primary biliary cirrhosis[J].J Hepatolo-gy, 2002, 35 (5) ∶1172-1178. -
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