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MMPs在肝纤维化形成与逆转过程中的作用

赵春洪 张晓岚

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MMPs在肝纤维化形成与逆转过程中的作用

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  • 中图分类号: R575.2

  • [1]Somerville RP, Oblander SA, Apte SS.Matrix metalloproteinases:old dogs with new tricks[J].Genome Biol, 2003, 4 (6) ∶216.
    [2]Leroy V, Monier F, Bottari S, et al.Circulating matrix metallopro-teinases 1, 2, 9 and their inhibitors TIMP-1 and TIMP-2 as serummarkers of liver fibrosis in patients with chronic hepatitis C:compari-son with PIIINP and hyaluronic acid[J].Am J Gastroenterol, 2004, 99 (2) ∶271-279.
    [3]Yan S, Chen GM, Yu CH, et al.Expression pattern of matrixmetal-loproteinases-13 in a rat model of alcoholic liver fibrosis[J].Hepa-tobiliary Pancreat Dis Int, 2005, 4 (4) ∶569-572.
    [4]Uchinami H, Seki E, Brenner DA, et al.Loss of MMP13 attenuatesmurine hepatic injury and fibrosis during cholestasis[J].Hepatolo-gy, 2006, 44 (2) ∶420-429.
    [5]Wang DR, Sato M, Li LN, et al.Stimulation of pro-MMP-2 pro-duction and activation by native form of extracellular type I collagenin hepatic stellate cells[J].Cell Struct Funct, 2003, 28 (6) ∶505-513.
    [6]Harty MW, Huddleston HM, Papa EF, et al.Repair after cholestaticliver injury correlates with neutrophil infiltration and matrix metallo-proteinase 8 activity[J].Surgery, 2005, 138 (2) ∶313-320.
    [7]Murata K, Kamata Y, Munakata H, et al.Immunohistochemicalstudy on liver fibrosis in biliary atresia[J].Hepatogastroenterology, 2008, 55 (81) ∶179-183.
    [8]Chen TY, Hsieh YS, Yang CC, et al.Relationship between matrixmetalloproteinase-2 activity and cystatin C levels in patients withhepatic disease[J].Clin Biochem, 2005, 38 (7) ∶632-638.
    [9]Watanabe T, Niioka M, Ishikawa A, et al.Dynamic change of cellsexpressing MMP-2 mRNA and MT1-MMP mRNA in the recoveryfrom liver fibrosis in the rat[J].J Hepatol, 2001, 35 (4) ∶465-473.
    [10]朱跃科, 王宝恩, 申凤俊, 等.实验性肝纤维化基质金属蛋白酶-2基因表达酶活性的变化[J].中华肝脏病杂志, 2005, 13 (7) ∶509-512.
    [11]Zhang LJ, Zheng WD, Chen YX, et al.Antifibrotic effects of inter-leukin-10 on experimental hepatic fibrosis[J].Hepatogastroenter-ology, 2007, 54 (79) ∶2092-2098.
    [12]Reif S, Somech R, Brazovski E, et al.Matrix metalloproteinases 2and 9 are markers of inflammation but not of the degree of fibrosis inchronic hepatitis C[J].Digestion, 2005, 71 (2) ∶124-130.
    [13]Han YP, Yan C, Zhou L, et al.Amatrix metalloproteinase-9 ac-tivation cascade by hepatic stellate cells in trans-differentiation inthe three-dimensional extracellular matrix[J].J Biol Chem, 2007, 282 (17) ∶12928-12939.
    [14]Han YP, Zhou L, Wang J, et al.Essential role of matrix metallo-proteinases in interleukin-1 induced myofibroblastic activation ofhepatic stellate cell in collagen[J].J Biol Chem, 2004, 279 (6) ∶4820-4828.
    [15]Xu GF, Li PT, Wang XY, et al.Dynamic changesinthe expression-of matrix metalloproteinases and their inhibitors, TIMPs, during he-patic fibrosis induced by alcohol in rats[J].World J Gastroenterol, 2004, 10 (24) ∶3621-3627.
    [16]Zhou X, Hovell CJ, Pawley S, et al.Expression of matrix metallo-proteinase-2 and-14 persists during early resolution of experimen-tal liver fibrosis and might contribute to fibrolysis[J].Liver Int, 2004, 24 (5) ∶492-501.
    [17]Iimuro Y, Nishio T, Morimoto T, et al.Delivery of matrix metallo-proteinase-1 attenuates established liver fibrosis in the rat[J].Gas-troenterology, 2003, 124 (2) ∶445-458.
    [18]Siller-Lopez F, Sandoval A, Salgado S, et al.Treatment with hu-man metalloproteinase-8 gene delivery ameliorates experimental ratliver cirrhosis[J].Gastroenterology, 2004, 126 (4) ∶1122-1133.
    [19]赵志海, 辛绍杰, 赵景民, 等.实验性肝纤维化逆转过程中基质金属蛋白酶表达动态研究[J].临床肝胆病杂志, 2007, 23 (1) ∶21-23.
    [20]Hemmann S, Graf J, Roderfeld M, et al.Expression of MMPs andTIMPs in liver fibrosis-a systematic review with special emphasison anti-fibrotic strategies[J].J Hepatol, 2007, 46 (5) ∶955-975.
    [21]Roderfeld M, Weiskirchen R, Wagner S, et al.Inhibition of hepat-ic fibrogenesis by matrix metalloproteinase-9 mutants in mice[J].FASEB J, 2006, 20 (3) ∶444-454.
    [22]Popov Y, Patsenker E, Stickel F, et al.Integrin alphavbeta6 is amarker of the progression of biliary and portal liver fibrosis and a no-vel target for antifibrotic therapies[J].J Hepatol, 2008, 48 (3) ∶453-464.
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  • 出版日期:  2009-03-20
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