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国产熊去氧胆酸治疗原发性胆汁性肝硬化患者的随访

高峰 张福奎 贾继东

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国产熊去氧胆酸治疗原发性胆汁性肝硬化患者的随访

详细信息
  • 中图分类号: R575.22

Liver function changes of ursodeoxycholic acid made in china for patients with primary biliary cirrhosis.

  • 摘要: 目的观察国产熊去氧胆酸对原发性胆汁性肝硬化患者肝功生化指标的影响。方法选择北京友谊医院经肝穿活检病理学或AMA-M2阳性而确诊的原发性胆汁性肝硬化患者,应用国产熊去氧胆酸(13-15)mg/kg day,分三次口服,定期(每隔3个月)复查肝功。结果从用药第三个月起,γ-GT、ALP、ALT、AST水平开始明显下降(P<0.05)。结论国产熊去氧胆酸可以改善原发性胆汁性肝硬化患者胆汁淤积相关指标(GGT、ALP),降低转氨酶(ALT、AST)水平。

     

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  • 出版日期:  2008-04-20
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