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[1]Cantley LC. The phosphoinositide 3-kinase pathway[J].Science, 2002, 296 (5573) ∶1655-1657. [2]Aytug S, Reich D, Sapiro LE, et al. Impaired IRS-1/PI3-kinase signaling in patients with HCV: a mechanismfor increased prevalence of type 2 diabetes[J].Hepatology, 2003, 38 (6) ∶1384-1392. [3]Kawaguchi T, Yoshida T, Harada M, et al.Hepatitis C virus down-regulates insulin receptor substrates 1 and 2 through up-regulationof suppressor of cytokine signaling 3[J].AmJ Pathol, 2004, 165 (5) ∶1499-1508. [4]Shintani Y, Fujie H, Miyoshi H, et al. Hepatitis C virus infection and diabetes: direct involvement of the virus in the development of insulin resistance[J].Gastroenterology, 2004, 126 (3) ∶840-848. [5]T-YTai, J-YLu, C-LChen, et al.Interferon-αreduces insu-lin resistance andβ-cell secretion in responders among patients withchronic hepatitis B and C[J].Journal of Endocrinology, 2003, 178∶457-465. -
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