中文English
ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R

留言板

尊敬的读者、作者、审稿人, 关于本刊的投稿、审稿、编辑和出版的任何问题, 您可以本页添加留言。我们将尽快给您答复。谢谢您的支持!

姓名
邮箱
手机号码
标题
留言内容
验证码

TGF-β受体与肝纤维化

张宁 郑勇

引用本文:
Citation:

TGF-β受体与肝纤维化

基金项目: 

兵团博士基金课题(05Jc08); 

详细信息
  • 中图分类号: R575.2

Research funding: 

 

  • [1]Bissell DM, Roulot D, George J.Transforming growth factor betaand the liver[J].Hepatology, 2001, 34∶859-867.
    [2]Steffen KM, Lidia T, Birgit L, et al.Identification of endoglin in rathepatic stellate cells:new insights into TGF-βreceptorsignaling[J].J Bid Chem, 2005, 280∶3078-3087.
    [3]苏先狮, 唐桂林, 罗如干, 等.正常及肝纤维化大鼠肝内Ⅰ型转化生长因子β受体表达[J].中华肝脏病杂志, 1999, 7 (2) ∶93.
    [4]张立煌, 刘翠雪, 姚航平, 等.转化生长因子-β1及其受体的表达与大鼠肝纤维化关系的研究[J].浙江大学学报 (医学版) , 2000, 29 (3) ∶97-100.
    [5]Kato J, Ido A, Hasuike S, et al.Transforming growth factorβin-duced stimulation of formation of collagen fiber network and anti-fi-brotic effort of taurine in an in vitro model of hepatic fibrosis[J].Hepatology Research, 2004, 30 (1) ∶34-41.
    [6]Leask A, Abraham DJ, Finlay DR, et al.Dysregulation of transfor-ming growth factor beta signaling in scleroderma:overexpression ofendoglin in cutaneous scleroderma fibroblasts[J].Arthritis Rheum, 2002, 46 (7) ∶1857-1865.
    [7]Calabrese F, Valente M, Giacometti C, et al.Parenchymal transfor-ming factorβ1:Its typeⅡreceptor and Smad signaling pathway cor-relate with inflammation and fibrosis in chronic liver disease of viraletiology[J].Gastroenterol Hepatol, 2003, 18∶1302-1308.
    [8]Ozawa S, Uchivama K, Nakamori M, et al.Combination gene thera-py of HGF and truncated typeⅡTGF-beta receptor for rat liver cir-rhosis after partial hepatectomy[J].World J Gastroenterol, 2005, 11 (15) ∶2269-2276.
    [9]汪玲, 胡国.TGF-βⅡ型受体部分基因表达质粒对实验性大鼠肝纤维化的影响[J].中华传染病杂志, 2002, 20 (30) ∶168-171.
    [10]蒋炜, 王吉耀.反义转化生长因子βⅠ型受体表达质粒对实验性肝纤维化的影响[J].中华医学杂志, 2002, 82 (17) ∶1160-1164.
    [11]蒋炜, 王吉耀.反义转化生长因子βⅡ型受体表达质粒对实验性肝纤维化的影响[J].中华肝脏病杂志, 2004, 12 (3) ∶137-140.
    [12]Ueno H, Sakamoto T, Nakamura T, et al.A soluble transforminggrowth factor beta receptor expressed in muscle prevents liver fibro-genesis and dysfunction in rats[J].Hum Gene Ther, 2000, 11 (1) ∶33-42.
    [13]Markowitz S, Wang J, Myeroff L, et al.Inactivation of the typeⅡTGF-beta receptor in colon cancer cells with microsatellite instabili-ty[J].Science, 1995, 268∶1336-1338.
    [14]Dooley S, Hamzavi J, Breitkopr K, et al.Smad7 prevents activa-tion of hepatic stellate cells and liver fibrosis in rats[J].Gastroenter-ology, 2003, 125 (1) ∶178-191.
    [15]Schnabl B, Kweon YO, Frederick JP, et al.The role of Smad3 inmediating mouse hepatic stellate cell activation[J].Hepatology, 2001, 34 (1) ∶89-100.
    [16]Zheng S, Chen A.Curcumin suppresses the expression of extracel-lular matrix genes in activated hepatic stellate cells by inhibiting geneexpression of connective tissue growth factor[J].Am J Physiol Gas-trointest Liver Physiol, 2006, 290∶883-893.
    [17]Nakamura T, Sakata R, Ueno T, et al.Inhibition of transforminggrowth factor beta prevents progression of liver fibrosis and enhanceshepatocyte regeneration in dimethylnitrosa mine-treated rats[J].Hepatology, 2000, 32 (2) ∶247-255.
    [18]De Gouville AC, Huet S.Inhibition of ALK5 as a newapproach totreat liver fibrotic diseases[J].Drug News Perspect, 2006, 19 (2) ∶85-90.
  • 加载中
计量
  • 文章访问数:  1984
  • HTML全文浏览量:  2
  • PDF下载量:  1213
  • 被引次数: 0
出版历程
  • 出版日期:  2008-01-20
  • 分享
  • 用微信扫码二维码

    分享至好友和朋友圈

目录

    /

    返回文章
    返回