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Therapy of chronic hepatitis B companied with alcoholic liver disease with Ganle
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摘要: 观察应用复方二氯醋酸二异丙胺治疗慢性病毒性肝炎合并酒精性肝损伤的临床疗效。选择确诊慢性病毒性肝炎合并酒精性肝损伤58例,随机分成两组。A组(n=30)在常规保肝治疗基础上,加用复方二氯醋酸二异丙胺(0.4~0.8)克溶于生理盐水中静脉滴注,每日一次;B组(n=28)常规保肝治疗,两组均4周为一疗程。两种药物临床总有效率分别为86.7%、64.3%,血清胆红素下降A组较B组明显(P<0.05)。复方二氯醋酸二异丙胺对改善慢性病毒性肝炎合并酒精性肝损伤症状和降低血清转氨酶有较好的疗效,伴有高胆红素血症患者应用复方二氯醋酸二异丙胺优于常规保肝治疗。
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关键词:
- 复方二氯醋酸二异丙胺 /
- 慢性病毒性肝炎合并酒精性肝损伤
Abstract: To evaluate the efficacy of diisopropylamine dichloroacetate (Ganle) injection on chronic hepatitis companied with alcoholic liver disease.58 patients with chronic hepatitis company with alcoholic liver disease were randomly divided into two groups.Group A (n=30) was treated with diisopropylamine dichloroacetate injection 0.4-0.8 gram each day, and group B (n=28) with routine liver protectant.The clinical efficient rates were 86.7% and 64.3% respectively.There were significant difference between the two groups (P<0.05) .And the level of TBil of group A decreased more significantly than that of group B (P<0.05) .These results suggested that diisopropylamine dichloroacetate injection was an effective and safe medicine on treating hepatitis B companied with alcoholic liver disease. -
[1] 中华医学会.病毒性肝炎防治方案[J].中华传染病杂志, 2001, 19∶57~62. [2]池肇春、叶维法.新编实用肝病学[M]北京:北京科技出版社, 1994∶487~488. [3] 王友永、史美浦、熊方武.病毒型肝炎药物专辑[M].北京:中国医药科技出版, 1994∶83~85. -
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