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Total ultrasonic scores to diagnosing early cirrhosis
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摘要: 探讨早期肝硬化的影像学特征。 10 2例慢性肝炎患者行B超、CT检查及肝穿刺活组织病理学检查 ,将超声、CT图象特征同病理组织学标准进行对照分析。随纤维化分期的加重 ,综合肝实质回声、肝表面、肝脏边缘、肝静脉、脾脏面积等 5项参数的超声总积分值逐渐升高。以超声总积分大于 10分为界值 ,诊断肝硬化的敏感性为86 1% ,特异性为 95 5 %。肝脏CT图象的形态学观察诊断肝硬化患者的特异性为 10 0 % ,敏感性为 4 8 5 %。综合多项超声参数而成的超声总积分对诊断早期肝硬化有较高的敏感性和特异性。CT诊断早期肝硬化虽然特异性较高 ,但敏感性较低Abstract: To investigate the imaging feature of early cirrhosis. 102 patients with chronic hepatitis were enrolled. Ultrasonography, CT were examined and compared with histological fibrotic stage. The higher the histological fibrotic stage, the greater the total ultrasonic scores including the parameters of liver surface, edge, parenchyma echogenicity, intrahepatic vessels, and the size of spleen. By receiver operating curve analysis, the sensitivity to distinguish cirrhosis from chronic hepatitis was 86.1% and specificity was 95.5% if the cu-off value of total ultrasonic score was more than 10. The specificity of CT imaging to diagnosis cirrhosis was 100%, but the sensitivity was only 48.5%. The total ultrasonic score had high specificity and sensitivity in diagnosing early cirrhosis. The characteristic CT imaging had high specificity but low sensitivity in diagnosing early cirrhosis.
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Key words:
- Cirrhosis /
- Ultrasonography /
- CT
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[1]病毒性肝炎防治方案[J].中华传染病杂志, 2001, 19 (1) ∶56-62. [2]ChristopheA , FredericO , NouriK , etal.Ultrasonographicdiagnosisofhepaticfibrosisorcirrhosis[J].JHepatology, 1999, 30∶479-484. [3]StefanoG , LauraG , NicolaV , etal.Whatisthecriterionfordifferenti atingchronichepatitisfromcompensatedcirrhosis?Aprospectivestudycomparingultrasonographyandpercutaneousliverbiopsy[J].JHepatolo gy, 1997, 27∶979-985. [4]FerralH , MaleR , CardielM , etal.Cirrhosis:Diagnosisbyliversurfaceanalysiswithhigh-frequencyultrasound[J].GastrointestRadiol, 1992, 17∶74-78. -
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