硫胺素与甘草酸二铵治疗慢性乙型肝炎的临床疗效分析

李永新; 高庆伟; Diana M Luan; Amy E. Wallace; 王英兰

硫胺素与甘草酸二铵治疗慢性乙型肝炎的临床疗效分析

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中图分类号: R512.62
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出版历程
- 出版日期: 2003-04-20

Analysis on clinical efficacy of Thiamine and Drammonium glycyrrhizinate concerning the treatment of chronic hepatitis B

摘要

摘要: 观察硫胺素与甘草酸二铵治疗慢性乙型肝炎的临床疗效。在美国加州及大连分别对慢性乙型肝炎患者应用硫胺素和甘草酸二铵。甘草酸二铵组与甘草酸二铵 +硫胺素组肝功复常率两组间有显著差异 ;硫铵素组与上述两组比较肝功复常率明显降低 ,差异显著。硫铵素组连续用药 4 8周后 ,肝功复常率、血清HBVDNA、HBeAg阴转率与治疗第八周结束时各治疗组比较有显著差异。硫铵素可降低乙肝病毒含量 ,稳定肝脏内环境 ,促进肝功恢复
- 慢性乙型肝炎 /
- 硫胺素 /
- 甘草酸二铵
Abstract: To observe the clinical efficacy of Thiamine and Diammonium glycyrrhizinate on chronic hepatitis B. patients of chronic hepatitis B were treated with Thiamine in California U.S.A and Dalian city respectively. Normalization rate of liver function showed significant difference between Diammonium glycyrrhizinate group and the group combined with Thiamine; compared with the above two groups the group of Thiamine showed apparent decrease in liver function normalization rate, with significance. At the end of the 48-week continuous treatment, normalization of liver function, negative conversion rate of HBVDNA and HBeAg in Thiamine group showed significant difference compared with the other groups at the end of the 8th week. Thiamine may decrease content of virus, stabilize hepatic internal environment, and promote recovery of liver function.
- chronic hepatitis B /
- Thiamine /
- Diammonium glycyrrhizinate

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参考文献(6)

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