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Experimental Studies of the Phamacologic and Toxical Effects of the Dingxiangye tablet
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摘要: 本文对丁香叶片的药理实验表明 ,该药能预防和治疗四氯化碳所引起的小鼠肝损伤模型 ,具有明显的降低SGPT的作用 ,并能保护肝脏对溴磺酞钠的排泄能力。急性和亚急性毒理实验表明 ,丁香叶片对肝、肾、脑及血液系统无明显毒副作用 ,是值得推广的治疗各种肝病的有效药物。Abstract: WT5”BZ]To study the protective effects of Dingxianye tablet on mouse liver lesson induced by CCl 4 Our studies shown that Dingxiangye tablet could provent and cure mouse liver damage induced by CCl 4, reduce the eleveted ALT in serum and protecte the secreating function of liver to bromsulphonein (BSP) The acute and subacute toxilogical study demon strated that dingxiangye tablet has no toxic effects on liver kidney, brain and blood system The present study suggests that Dingxiangye tablet can be used in treatment of various liver disease [WT5”HZ]
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〔1〕张光年 , 等 生物化学与检测技术 , 人民卫生出版社 , 1981, pp82 3 〔2〕白求恩医科大学传染科 丁香叶片的制备及对急性黄疸性肝炎43 4例的临床疗效 , 中草药通讯 , 1978, ( 1) 2 3 []〔3〕王丹丹等 紫丁香有效成分的研究 , 药学学报 , 1980 , 17 ( 12 ) 982 -
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