自身免疫性肝炎非激素疗法的研究进展

钟启华; 周桂琴; 王宪波; 王晓静; 王融冰; 孙凤霞

doi:10.3969/j.issn.1001-5256.2016.02.040

自身免疫性肝炎非激素疗法的研究进展

DOI: 10.3969/j.issn.1001-5256.2016.02.040

1. 首都医科大学附属北京地坛医院
2. 北京中医药大学
3. 首都医科大学附属北京中医医院

基金项目:

北京市中医药科技发展资金项目(JJ2013-14)；

详细信息

中图分类号: R575.1
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- 被引次数: 0
出版历程
- 收稿日期: 2015-06-12
- 出版日期: 2016-02-20

Research advances in non-hormonal therapies for autoimmune hepatitis

Beijing Ditan Hospital,Capital Medical University

Research funding:

摘要

摘要: 自身免疫性肝炎是由异常自身免疫反应介导的慢性进行性肝脏炎症性疾病。其治疗以免疫抑制治疗为主,晚期可行肝移植,目前国际上公认的标准治疗措施为泼尼松或泼尼松联合硫唑嘌呤,大部分患者能达到临床缓解,但其复发率高且有部分患者治疗无效。简述了激素治疗之外的治疗措施及治疗失败后的替代疗法,并介绍了中西医结合疗法在自身免疫性肝炎中的应用,表明了非激素疗法是未来自身免疫性肝炎治疗的新方向,但仍需进一步探索。
- 肝炎,自身免疫性 /
- 免疫抑制剂 /
- 中西医结合疗法 /
- 综述
Abstract: Autoimmune hepatitis is a chronic progressive inflammatory disease of the liver,which is mediated by the abnormal autoimmune response. Immunosuppressive therapy is the major therapeutic method for this disease,and liver transplantation can be performed for patients in the advanced stage. At present,the internationally acknowledged standard therapeutic method is prednisone or prednisone combined with azathioprine. Most patients can achieve clinical remission,but the recurrence rate is high and some patients fail to respond to the treatment.This article briefly reviews the therapies except corticosteroid therapy and substitutive therapy after treatment failure,introduces the application of integrated traditional Chinese and Western medicine therapy for autoimmune hepatitis,and points out that non- hormonal therapies are the new directions for the treatment of autoimmune hepatitis,which still needs to be further investigated.
- hepatitis,autoimmune /
- immunosuppressive agents /
- TCM WM therapy /
- review

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参考文献(26)

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