中文English
ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R

留言板

尊敬的读者、作者、审稿人, 关于本刊的投稿、审稿、编辑和出版的任何问题, 您可以本页添加留言。我们将尽快给您答复。谢谢您的支持!

姓名
邮箱
手机号码
标题
留言内容
验证码

肝性脑病患者的营养支持治疗

甘雪梅 李武

引用本文:
Citation:

肝性脑病患者的营养支持治疗

DOI: 10.3969/j.issn.1001-5256.2016.01.039
详细信息
  • 中图分类号: R575.3

Nutrition support therapy for patients with hepatic encephalopathy

  • 摘要: 肝性脑病是肝衰竭最常见的并发症之一,在住院患者中发病率高,而大多数肝性脑病患者存在不同程度的营养不良。近年来,越来越多的临床试验证实了营养支持治疗对肝性脑病的治疗是有益的,因此营养治疗正逐渐被得到重视。介绍了肝性脑病发生营养不良的机制,并对肝性脑病患者的营养评估和营养治疗方式进行了概述。

     

  • [1]VILSTRUP H,AMODIO P,BAJAJ J,et al.Hepatic encephalopathy in chronic liver disease:2014 practice guideline by the American Association for the Study of Liver Diseases and the European Association for the Study of the Liver[J].Hepatology,2014,60(2):715-735.
    [2]Chinese Society of Gastroenterology and Chinese Society of Hepatology,Chinese Medical Association.Comem on thediagnosis andtreatment of hepatic encephalopathy in China(Chongqing,2013)[J].Chin J Hepatol,2013,21(9):641-651.(in Chinese)中华医学会消化病学分会,中华医学会肝病学分会.中国肝性脑病诊治共识意见(2013年,重庆)[J].中华肝脏病杂志,2013,21(9):641-651.
    [3]HOU Y.The clinical comparison of cirrhosis patients with different etiological upper digestive tract hemorrhage[J].J Clin Exp Med,2015,14(12):999-1001.(in Chinese)侯昀.肝硬化不同病因上消化道出血患者的临床对比[J].临床和实验医学杂志,2015,14(12):999-1001.
    [4]CABRAL CM,BURNS DL.Low-protein diets for hepatic encephalopathy debunked:let them eat steak[J].Nutr Clin Pract,2011,26(2):155-159.
    [5]AMODIO P,BEMEUR C,BUTTERWORTH R,et al.The nutritional management of hepatic encephalopathy in patients with cirrhosis:International Society for Hepatic Encephalopathy and Nitrogen Metabolism Consensus[J].Hepatology,2013,58(1):325-336.
    [6]PERES WA,LENTO DF,BALUZ K,et al.Phase angle as a nutritionalevaluation tool in all stages of chronic liver disease[J].Nutr Hosp,2012,27(6):2072-2078.
    [7]PLAUTH M,CABRE E,RIGGIO O,et al.ESPEN guidelines on enteral nutrition:liver disease[J].Clin Nutr,2006,25(2):285-294.
    [8]TSIEN CD,McC ULLOUGH AJ,DASARATHY S.Late evening snack:exploiting a period of anabolic opportunity in cirrhosis[J].J Gastroenterol Hepatol,2012,27(3):430-441.
    [9]Chinese Society of Critical Care Medicine,Chinese Medical Association.Guidelines on nutritional support for critically ill patients[J].Chin Critical Care Med,2006,18(10):582-590.(in Chinese)中华医学会重症医学分会.危重患者营养支持指导意见[J].中国危重病急救医学,2006,18(10):582-590.
    [10]CORDOBA J,LOPEZ-HELLIN J,PLANAS M,et al.Normal protein diet for episodic hepatic encephalopathy:results of a randomized study[J].Hepatol,2004,41(1):38-43.
    [11]SIMN-TALERO M,GARCA-MARTNEZ R,TORRENS M,et al.Effects of intravenous albumin in patients with cirrhosis and episodic hepatic encephalopathy:a randomized double-blind study[J].J Hepatol,2013,59(6):1184-1192.
    [12]LES I,DOVAL E,GARCIA-MARTINEZ R,et al.Effects of branched-chain amino acids supplementation in patients with cirrhosis and a previous episode of hepatic encephalopathy:a randomized study[J].Am J Gastroenterol,2011,106(6):1081-1088.
    [13]GLUUD LL,DAM G,BORRE M,et al.Oral branched-chain amino acids have a beneficial effect on manifestations of hepatic encephalopathy in a systematic review with meta-analyses of randomized controlled trials[J].J Nutr,2013,143(8):1263-1268.
    [14]KAWAGUCHI T,SHIRAISHI K,ITO T,et al.Branched-chain amino acids prevent hepatocarcinogenesis and prolong survival of patients with cirrhosis[J].Clin Gastroenterol Hepatol,2014,12(6):1012-1018.
    [15]LEISE MD,POTERUCHA JJ,KAMATH PS,et al.Management of hepatic encephalopathy in the hospital[J].Mayo Clin Proc,2014,89(2):241-253.
    [16]SHARMA P,SHARMA BC,AGRAWAL A,et al.Primary prophylaxis of overt hepatic encephalopathy in patients with cirrhosis:an open labeled randomized controlled trial of lactulose versus no lactulose[J].J Gastroenterol Hepatol,2012,27(8):1329-1335.
    [17]JAIN L,SHARMA BC,SRIVASTAVA S,et al.Serum endotoxin,inflammatory mediators,and magnetic resonance spectroscopy before and after treatment in patients with minimal hepatic encephalopathy[J].J Gastroenterol Hepatol,2013,28(7):1187-1193.
    [18]SHARMA BC,SHARMA P,LUNIA MK,et al.A randomized,double-blind,controlled trial comparing rifaximin plus lactulose with lactulose alone in treatment of overt hepatic encephalopathy[J].Am J Gastroenterol,2013,108(9):1458-1463.
    [19]BAJAJ JS,RIDLON JM,HYLEMON PB,et al.Linkage of gut microbiome with cognition in hepatic encephalopathy[J].Am J Physiol Gastrointest Liver Physiol,2012,302(1):g168-g175.
    [20]LUNIA MK,SHARMA BC,SHARMA P,et al.Probiotics prevent hepatic encephalopathy in patients with cirrhosis:a randomized controlled trial[J].Clin Gastroenterol Hepatol,2014,12(6):1003-1008.
    [21]AGRAWAL A,SHARMA BC,SHARMA P,et al.Secondary prophylaxis of hepatic encephalopathy in cirrhosis:an open-label,randomized controlled trial of lactulose,probiotics,and no therapy[J].Am J Gastroenterol,2012,107(7):1043-1050.
    [22]QURESHI MO,KHOKHAR N,SALEEM A,et al.Correlation of hyponatremia with hepatic encephalopathy and severity of liver disease[J].J Coll Physicians Surg Pak,2014,24(2):135-137.
    [23]LIU HL.Relationship between hyponatremia and main complications in patients with decompensated cirrhosis[J].J Clin Exp Med,2015,14(17):1448-1450.(in Chinese)刘红凌.肝硬化失代偿期患者低钠血症与其他并发症相关性研究[J].临床和实验医学杂志,2015,14(17):1448-1450.
    [24]LOPES PJ,MEI MF,GUARDIA AC,et al.Correlation between serum magnesium levels and hepatic encephalopathy in immediate post liver transplantation period[J].Transplant Proc,2013,45(3):1122-1125.
    [25]CHAVEZ-TAPIA NC,CESAR-ARCE A,BARRIENTOS-GUTIERREZ T,et al.A systematic review and meta-analysis of the use of oral zinc in the treatment of hepatic encephalopathy[J].Nutr J,2013,12:74.
    [26]RIVERA-MANCIA S,RIOS C,MONTES S.Manganese accumulation in the CNS and associated pathologies[J].Biometals,2011,24(5):811-825.
  • 加载中
计量
  • 文章访问数:  2476
  • HTML全文浏览量:  40
  • PDF下载量:  488
  • 被引次数: 0
出版历程
  • 收稿日期:  2015-04-07
  • 出版日期:  2016-01-20
  • 分享
  • 用微信扫码二维码

    分享至好友和朋友圈

目录

    /

    返回文章
    返回