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Research progress in hepatic myelopathy
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摘要:
肝性脊髓病是多种急慢性肝脏疾病引起的一种较为少见的神经系统并发症,临床上以进行性双下肢痉挛性截瘫为特征性表现。该病发病机制尚不明确,缺乏有效治疗方法,且预后不良。通过回顾相关文献,对其发病机制、病理研究、临床诊断标准及治疗进行综述,指出应加强对其发病机制的研究,进行大样本量、长期随访的临床研究,以提供较可靠的循证医学证据。
Abstract:Hepatic myelopathy is a rare neurological complication which is caused by various acute or chronic liver diseases. It is clinically characterized by progressive spastic paraplegia of both lower extremities. The pathogenesis of this disease is unclear,and there is a lack of effective treatments as well as poor prognosis for this disease. By reviewing the relevant literature,the pathogenesis,pathological studies,clinical diagnosis criteria,and treatment of the disease are summarized. It is necessary to strengthen the study of pathogenesis of the disease as well as the clinical study of large sample size and long- term follow- up,thus providing reliable evidence for evidence- based medicine.
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Key words:
- liver diseases /
- spinal cord diseases /
- review
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