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慢加急性肝衰竭的诊断标准比较及预后判断模型进展
Research advances in diagnostic criteria for acute-on-chronic liver failure and models for prognostic evaluation
文章发布日期:2019年05月13日  来源:  作者:刘娟,白飞云,张晶  点击次数:629次  下载次数:131次

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【摘要】:慢加急性肝衰竭是在慢性肝病基础上出现严重急性肝功能失代偿,近期病死率极高,一直是肝病领域的研究热点。近年来中国、亚太和欧洲肝病学会分别出台或更新了慢加急性肝衰竭的诊断标准,但因东西方患者病因不同、发病机制不同导致诊断标准差异巨大。基于不同的诊断标准,预后判断模型也不断更新。对比了上述诊断标准并分析其共同点及差异,同时对新的预后判断模型进行详细的介绍,以便临床医生更好地理解和诊治该疾病。
【Abstract】:Acute-on-chronic liver failure is a serious acute liver function decompensation based on chronic liver diseases. It has an extremely high short-term mortality rate and has always been a research hotspot in the field of liver disease. In recent years, China, Asian Pacific Association for the Study of the Liver, and European Association for the Study of the Liver have issued or updated the diagnostic criteria for acute-on-chronic liver failure, but the diagnostic criteria vary greatly due to different etiologies and pathogeneses in the East and the West. Prognostic models have also been constantly updated based on different diagnostic criteria. This article compares the above diagnostic criteria and introduces the new prognostic models in detail, in order to improve the understanding and diagnosis/treatment of this disease among clinicians.
【关键字】:慢加急性肝功能衰竭; 诊断; 预后; 综述
【Key words】:acute-on-chronic liver failure; diagnosis; prognosis; review
【引证本文】:LIU J, BAI FY, ZHANG J. Research advances in diagnostic criteria for acute-on-chronic liver failure and models for prognostic evaluation[J]. J Clin Hepatol, 2019, 35(6): 1384-1387. (in Chinese)
刘娟, 白飞云, 张晶. 慢加急性肝衰竭的诊断标准比较及预后判断模型进展[J]. 临床肝胆病杂志, 2019, 35(6): 1384-1387.

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