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饮酒对慢性乙型肝炎患者疾病进展和抗病毒治疗的影响
Influence of drinking on progression of chronic hepatitis B and outcome of antiviral therapy
文章发布日期:2019年02月03日  来源:  作者:刘晨,邢卉春,成军,等  点击次数:302次  下载次数:106次

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【摘要】:HBV与酒精可以通过多种机制相互影响导致肝损伤。大量饮酒可以使慢性乙型肝炎(CHB)患者的疾病进展更为迅速且预后更差,同时严重影响抗病毒治疗效果和依从性。我国CHB患者饮酒的流行病学情况尚不明确,HBV与酒精的相互影响机制尚需进一步明确。临床上,仍需进一步规范CHB患者的戒酒管理,尽可能减轻酒精导致的肝损伤。
【Abstract】:HBV can interact with alcohol in various ways to cause liver damage. Heavy drinking can accelerate the progression of chronic hepatitis B and lead to a poorer prognosis; meanwhile, it can also affect the outcome and compliance in patients receiving antiviral therapy. The epidemiology of drinking in patients with chronic hepatitis B in China remains unclear, and further studies are needed to clarify the mechanism of interaction between alcohol and HBV. Drinking management should be strengthened in patients with chronic hepatitis B in clinical practice, in order to alleviate liver injury induced by alcohol.
【关键字】:肝炎, 乙型, 慢性; 肝疾病, 酒精性; 饮酒; 流行病学; 病理过程; 治疗结果
【Key words】:hepatitis B, chronic; liver diseases, alcoholic; alcohol drinking; epidemiology; pathologic processes; treatment outcome
【引证本文】:LIU C, XING HC, CHENG J, et al. Influence of drinking on progression of chronic hepatitis B and outcome of antiviral therapy[J]. J Clin Hepatol, 2019, 35(3): 472-475. (in Chinese)
刘晨, 邢卉春, 成军, 等. 饮酒对慢性乙型肝炎患者疾病进展和抗病毒治疗的影响[J]. 临床肝胆病杂志, 2019, 35(3): 472-475.

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